80028-75-7

Basic information

• Product Name: 2-(2-(2-(tert-butoxycarbonylamino)ethyl)-5-chloro-1H-benzo[d]imidazol-1-yl)ethyl 4-methylbenzene-sulfonate
• Synonyms: 2-(2-(2-(tert-butoxycarbonylamino)ethyl)-5-chloro-1H-benzo[d]imidazol-1-yl)ethyl 4-methylbenzene-sulfonate
• CAS NO: 80028-75-7
• Molecular Weight: 494.011
• Mol File: 80028-75-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(2-(2-(tert-butoxycarbonylamino)ethyl)-5-chloro-1H-benzo[d]imidazol-1-yl)ethyl 4-methylbenzene-sulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-(2-(tert-butoxycarbonylamino)ethyl)-5-chloro-1H-benzo[d]imidazol-1-yl)ethyl 4-methylbenzene-sulfonate(80028-75-7)
• EPA Substance Registry System: 2-(2-(2-(tert-butoxycarbonylamino)ethyl)-5-chloro-1H-benzo[d]imidazol-1-yl)ethyl 4-methylbenzene-sulfonate(80028-75-7)

Safety Data

• Hazardous Substances Data: 80028-75-7(Hazardous Substances Data)

Upstream product

• 80028-71-3 2-(2-aminoethyl)-5-chloro-1-(2-hydroxyethyl)benzimidazole dihydrochloride 
• 33141-10-5 5-chloro-2-<(2-hydroxyethyl)amino>aniline 
• 59320-13-7 2-(4-chloro-2-nitrophenylamino)ethanol 
• 80028-73-5 2-<2-<(tert-butoxycarbonyl)amino>ethyl>-5-chloro-1-(2-hydroxyethyl)benzimidazole 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1239879-60-7 C₁₈H₂₀ClN₃O₃S 

Relevant articles and documents

HISTAMINE H3 INVERSE AGONISTS AND ANTAGONISTS AND METHODS OF USE THEREOF

Provided herein are fused imidazolyl compounds, methods of synthesis, and methods of use thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders and metabolic disorders. Compounds provided herein inhibit the activity of histamine H3 receptors and modulate the release of various neurotransmitters, such as histamine, acetylcholine, norepinephrine, and dopamine (e.g. at the synapse). Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.