80200-20-0

Basic information

• Product Name: 1H-Pyrazole-1-ethanol, 4-methylbenzenesulfonate (ester)
• CAS NO: 80200-20-0
• Molecular Formula: C12H14N2O3S
• Molecular Weight: 266.321
• Mol File: 80200-20-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazole-1-ethanol, 4-methylbenzenesulfonate (ester)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-1-ethanol, 4-methylbenzenesulfonate (ester)(80200-20-0)
• EPA Substance Registry System: 1H-Pyrazole-1-ethanol, 4-methylbenzenesulfonate (ester)(80200-20-0)

Safety Data

• Hazardous Substances Data: 80200-20-0(Hazardous Substances Data)

Upstream product

• 6314-23-4 1-(2-hydroxyethyl)-pyrazole 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 120070-51-1 1-[2-(1H-pyrazol-1-yl)ethyl]-4-(4-methyl-thiazol-2-yl)-4-(N-phenylpropionamido)piperidine 
• 80200-23-3 1-isopropylamino-3-[4-[2-(1-pyrazolyl)ethoxy]phenoxy]-2-propanol 
• 689157-81-1 1-(2-azidoethyl)-1H-pyrazole 
• 80200-52-8 1-isopropylamino-3-[4-[2-(1-pyrazolyl)ethylthio]phenoxy]-2-propanol 
• 167960-75-0 1-[2-(ethylamino)ethyl]-3,5-dimethylpyrazole 
• 131727-13-4 N-(phenyl)-N-[1-(2-(1H-pyrazol-1-yl)ethyl)-4-methoxycarbonyl-4-piperidinyl]propanamide 
• 131727-15-6 N-(phenyl)-N-[1-(2-(1H-pyrazol-1-yl)ethyl)-4-methoxymethyl-4-piperidinyl]propanamide 
• 80200-14-2 4-[2-(1-pyrazolyl)ethylthio]phenol 

Relevant articles and documents

AMIDE COMPOUNDS

A compound of the formula (I) wherein R1 is hydrogen, lower alkyl, lower alkenyl, halo(lower)alkyl, cyclo(lower)alkyl, lower alkoxy, lower alkylthio, acyl, optionally substituted aryl or NR3R4; R2 is hydrogen; or aryl or heteroaryl, each of which may be substituted; X is direct bond or bivalent residue derived from piperazine; Y is -(A1)n#191-(A2?)?m#191-, wherein n and m are independently 0 or 1); is bivalent residue derived from arene or heteroarene; and is bivalent residue derived from arene or heteroarene, or a salt thereof. The compound of the present invention and a salt thereof inhibit apolipoprotein B (Apo B) secretion and are useful as a medicament for prophylactic and treatment of diseases or conditions resulting from elevated circulating levels of Apo B.

SUBSTITUTED PHENOXY-AMINOPROPANOL DERIVATIVES

Phenoxy-aminopropanol derivatives of the formula STR1 wherein R is lower alkyl, X is oxygen or sulfur, n is the integer zero or 1, Y is methylene, ethylene or propylene or, when n is zero, Y can also be a group of the formula EQU1 , wherein the double-bond is trans and the carbon atom marked with an asterisk is linked to Z, and Z is a 5-membered aromatic heterocyclic ring which contains one or more nitrogen atoms as the sole hetero atom (s), said heterocyclic ring is linked to Y via a nitrogen atom, and may be substituted by halogen, lower alkyl, lower alkoxy, aryl, cyano or carboxamido, or on adjacent carbon atoms by a group of the formula STR2 and pharmaceutically acceptable acid addition salts thereof are described. A process for the preparation of the compound of formula I and pharmaceutical preparations containing them are also described. The aforementioned compounds and salts possess β-adrenergic blocking activity and antihypertensive activity.