80258-61-3Relevant articles and documents
MACROCYCLES AS KINASE INHIBITORS
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Page/Page column 69; 70, (2014/12/09)
Compounds of the formula I in which X, Y, Q1, M, Q2 and B have the meanings indicated in Claim 1, are inhibitors of GCN2, and can be employed, inter alia, for the treatment of cancer.
Novel CD40 : CD154 binding interruptor compounds and use thereof to treat immunological complications
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Page/Page column 22-23, (2010/11/30)
The present invention relates to novel CD40:CD154 binding interrupter compounds and use of these compounds and pharmaceutical compositions comprising them, to treat conditions associated with inappropriate CD154 activation in a subject. Specifically, this
Synthesis and pharmacological studies of N-substituted 6-[(2- aminoethyl)amino]-1,3-dimethyl-2,4(1H,3H)-pyrimidinediones, novel class III antiarrhythmic agents
Katakami,Yokoyama,Miyamoto,Mori,Kawauchi,Nobori,San-nohe,Kaiho,Kamiya
, p. 3325 - 3330 (2007/10/02)
A series of 6-[(2-aminoethyl)amino]-1,3-dimethyl-2,4(1H,3H)- pyrimidinedione derivatives were synthesized and studied for their class III electrophysiological activity and class II (β-blocking) effects in in vitro and in vivo models. Structure-activity re