803686-19-3

Basic information

• Product Name: Ethanone, 1-[4-bromo-7-(1-phenylethoxy)-2-benzofuranyl]-
• CAS NO: 803686-19-3
• Molecular Formula: C18H15BrO3
• Molecular Weight: 359.219
• Mol File: 803686-19-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[4-bromo-7-(1-phenylethoxy)-2-benzofuranyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[4-bromo-7-(1-phenylethoxy)-2-benzofuranyl]-(803686-19-3)
• EPA Substance Registry System: Ethanone, 1-[4-bromo-7-(1-phenylethoxy)-2-benzofuranyl]-(803686-19-3)

Safety Data

• Hazardous Substances Data: 803686-19-3(Hazardous Substances Data)

Upstream product

• 803686-18-2 2-acetyl-4-bromo-7-hydroxybenzo[b]furan 
• 40020-87-9 2-acetyl-7-hydroxybenzofuran 
• 585-71-7 (1-bromoethyl)benzne 

Relevant articles and documents

BENZOFURAN COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME

The present invention relates to a benzofuran compound of the formula (I) wherein each symbol is as defined in the description, a pharmaceutically acceptable salt thereof and the like. The compound of the present invention has superior leukotriene inhibitory action, BLT2 competitive inhibitory action, BLT2 blocking action, action for the prophylaxis or treatment of allergy, action for the prophylaxis or treatment of asthma and action for the prophylaxis or treatment of inflammation, and is useful as an agent for the prophylaxis or treatment of diseases such as allergic disease, asthma, inflammation and the like, and other diseases.

Preparation of 2- And 4-(2-alkylcarbamoyl-1-methylvinyl)-7-alkyloxybenzo[b]furans having potent antagonistic activity against human leukotriene B4 BLT1 and/or BLT2 receptors

(E)-2- Acetyl-4-(2-diethylcarbamoyl-1-methylvinyl)-7-(1-phenylethoxy)benzo[b]furan (4b) with a characteristic conformation and (E)-2-(2-morpholinocarbo-1-methyl-vinyl)-7-ethoxycarbopropoxybenzo[b]furan ((E)-3b) were prepared and evaluated for their leukot