80396-67-4

Basic information

• Product Name: 1,5-bis-(3-amino-phenyl)-penta-1,4-dien-3-one
• Synonyms: 1,5-bis-(3-amino-phenyl)-penta-1,4-dien-3-one
• CAS NO: 80396-67-4
• Molecular Weight: 264.327
• Mol File: 80396-67-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,5-bis-(3-amino-phenyl)-penta-1,4-dien-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-bis-(3-amino-phenyl)-penta-1,4-dien-3-one(80396-67-4)
• EPA Substance Registry System: 1,5-bis-(3-amino-phenyl)-penta-1,4-dien-3-one(80396-67-4)

Safety Data

• Hazardous Substances Data: 80396-67-4(Hazardous Substances Data)

Upstream product

• 621-21-6 (1E,4E)-1,5-bis(3-nitrophenyl)penta-1,4-dien-3-one 
• 621-21-6 1,5-bis-(3-nitro-phenyl)-penta-1,4-dien-3-one 

Downstream Products

• 1228557-74-1 N,N'-{[(1E,4E)-3-oxopenta-1,4-diene-1,5-diyl]-di-3,1-phenylene}bis(2-bromoacrylamide) 

Relevant articles and documents

Symmetrical α-bromoacryloylamido diaryldienone derivatives as a novel series of antiproliferative agents. Design, synthesis and biological evaluation

In a continuing study of hybrid compounds containing the α-bromoacryloyl moiety as potential anticancer drugs, we synthesized a novel series of hybrids 4a-h, in which this moiety was linked to a 1,5-diaryl-1,4-pentadien-3-one system. Many of the conjugates prepared (4b, 4c, 4e and 4g) demonstrated pronounced, submicromolar antiproliferative activity against four cancer cell lines. Moreover, compound 4b induced apoptosis through the mitochondrial pathway and activated caspase-3 in a concentration-dependent manner.