80429-41-0

Basic information

• Product Name: 2-{2-[4-(3-methoxyphenyl)piperazin-1-yl]ethyl}-1-(1-methylethyl)-1H-naphtho[1,2-d]imidazole 2-hydroxypropane-1,2,3-tricarboxylate (salt)
• CAS NO: 80429-41-0
• Molecular Formula: C₃₃H₄₀N₄O₈
• Molecular Weight: 620.6927
• Mol File: 80429-41-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 639.3°C at 760 mmHg
• Flash Point: 340.5°C
• Vapor Pressure: 3.04E-16mmHg at 25°C
• CAS DataBase Reference: 2-{2-[4-(3-methoxyphenyl)piperazin-1-yl]ethyl}-1-(1-methylethyl)-1H-naphtho[1,2-d]imidazole 2-hydroxypropane-1,2,3-tricarboxylate (salt)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{2-[4-(3-methoxyphenyl)piperazin-1-yl]ethyl}-1-(1-methylethyl)-1H-naphtho[1,2-d]imidazole 2-hydroxypropane-1,2,3-tricarboxylate (salt)(80429-41-0)
• EPA Substance Registry System: 2-{2-[4-(3-methoxyphenyl)piperazin-1-yl]ethyl}-1-(1-methylethyl)-1H-naphtho[1,2-d]imidazole 2-hydroxypropane-1,2,3-tricarboxylate (salt)(80429-41-0)

Safety Data

• Hazardous Substances Data: 80429-41-0(Hazardous Substances Data)

Usage

Chemical structure

The compound contains a piperazine ring and an imidazole ring, which are both heterocyclic aromatic rings.

Functional groups

The presence of a hydroxypropane-1,2,3-tricarboxylate salt suggests that the compound has multiple carboxyl groups (-COOH) and a hydroxyl group (-OH).

Alkyl substituents

The compound has an ethyl group (-CH2CH3) attached to the piperazine ring and a 1-methylethyl (isopropyl) group (-CH(CH3)2) attached to the naphtho[1,2-d]imidazole core.

Aryl substituent

A 3-methoxyphenyl group (-Ar-OCH3) is attached to the piperazine ring, which may influence the compound's biological activity and pharmacokinetic properties.

Potential pharmaceutical applications

The presence of piperazine and imidazole moieties indicates that the compound may be involved in various biological activities, making it a potential candidate for pharmaceutical development.

Further research and testing

The exact uses and properties of this compound would need to be determined through additional research, experimentation, and analysis.

Salt form

The compound is presented as a salt, which can affect its solubility, stability, and bioavailability compared to its parent compound.

Upstream product

• 5949-29-1 citric acid monohydrate 
• 80429-40-9 2-[2-[4-(3-methoxyphenyl)-1-piperazinyl]ethyl]-1-(1-methylethyl)-1H-naphth[1,2-d]imidazole 

Relevant articles and documents

Anti-hypertensives: 1-alkyl-2-arylpiperazinoethyl-1H-naphthimidazoles

L 15848 (8b citrate) is a new anti-hypertensive agent belonging to the class of 1-alkyl-2-aminoethylnaphthimidazoles.It lowers blood pressure in spontaneously hypertensive rats (50 mg/kg, p.o.) and in conscious normotensive and renal hypertensive d