80429-43-2

Basic information

• Product Name: 1-(1-methylethyl)-2-(2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethyl)-1H-naphtho[1,2-d]imidazole 2-hydroxypropane-1,2,3-tricarboxylate (salt)
• CAS NO: 80429-43-2
• Molecular Formula: C₃₃H₃₇F₃N₄O₇
• Molecular Weight: 658.6647
• Mol File: 80429-43-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 613°C at 760 mmHg
• Flash Point: 324.5°C
• Vapor Pressure: 5.79E-15mmHg at 25°C
• CAS DataBase Reference: 1-(1-methylethyl)-2-(2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethyl)-1H-naphtho[1,2-d]imidazole 2-hydroxypropane-1,2,3-tricarboxylate (salt)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-methylethyl)-2-(2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethyl)-1H-naphtho[1,2-d]imidazole 2-hydroxypropane-1,2,3-tricarboxylate (salt)(80429-43-2)
• EPA Substance Registry System: 1-(1-methylethyl)-2-(2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethyl)-1H-naphtho[1,2-d]imidazole 2-hydroxypropane-1,2,3-tricarboxylate (salt)(80429-43-2)

Safety Data

• Hazardous Substances Data: 80429-43-2(Hazardous Substances Data)

Usage

Description

1-(1-methylethyl)-2-(2-4-[3-(trifluoromethyl)phenyl]piperazin-1-ylethyl)-1H-naphtho[1,2-d]imidazole 2-hydroxypropane-1,2,3-tricarboxylate (salt) is a complex chemical compound that belongs to the class of naphthoimidazole derivatives. It features a naphthoimidazole core with an isopropyl group and a piperazine moiety, and is salted with 2-hydroxypropane-1,2,3-tricarboxylic acid. 1-(1-methylethyl)-2-(2-4-[3-(trifluoromethyl)phenyl]piperazin-1-ylethyl)-1H-naphtho[1,2-d]imidazole 2-hydroxypropane-1,2,3-tricarboxylate (salt) holds significant interest in medicinal chemistry and pharmaceutical research due to its potential biological activities and therapeutic applications.

Uses

Used in Pharmaceutical Research:
1-(1-methylethyl)-2-(2-4-[3-(trifluoromethyl)phenyl]piperazin-1-ylethyl)-1H-naphtho[1,2-d]imidazole 2-hydroxypropane-1,2,3-tricarboxylate (salt) is used as a compound in pharmaceutical research for its potential biological activities and therapeutic applications. Its unique structure and properties make it a promising candidate for the development of new drugs and therapies.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-(1-methylethyl)-2-(2-4-[3-(trifluoromethyl)phenyl]piperazin-1-ylethyl)-1H-naphtho[1,2-d]imidazole 2-hydroxypropane-1,2,3-tricarboxylate (salt) is used as a key component in the design and synthesis of novel drugs. Its structural features allow for targeted modifications and optimization to enhance its pharmacological properties and efficacy.
Used in Drug Delivery Systems:
1-(1-methylethyl)-2-(2-4-[3-(trifluoromethyl)phenyl]piperazin-1-ylethyl)-1H-naphtho[1,2-d]imidazole 2-hydroxypropane-1,2,3-tricarboxylate (salt) may also be utilized in the development of drug delivery systems. Its properties could be harnessed to improve the delivery, bioavailability, and therapeutic outcomes of various pharmaceutical agents, particularly in the context of targeted drug delivery and controlled release applications.
Used in Chemical Synthesis:
In the broader field of chemical synthesis, 1-(1-methylethyl)-2-(2-4-[3-(trifluoromethyl)phenyl]piperazin-1-ylethyl)-1H-naphtho[1,2-d]imidazole 2-hydroxypropane-1,2,3-tricarboxylate (salt) serves as a versatile building block for the creation of a wide range of chemical compounds. Its unique structure can be further modified and functionalized to produce new molecules with diverse applications across various industries.
Used in Analytical Chemistry:
1-(1-methylethyl)-2-(2-4-[3-(trifluoromethyl)phenyl]piperazin-1-ylethyl)-1H-naphtho[1,2-d]imidazole 2-hydroxypropane-1,2,3-tricarboxylate (salt) can be employed in analytical chemistry as a reference compound or standard for the development and validation of analytical methods. Its distinct chemical properties make it suitable for use in various chromatographic, spectroscopic, and other analytical techniques.

Upstream product

• 5949-29-1 citric acid monohydrate 
• 80429-42-1 2-[2-[4-(3-trifluoromethylphenyl)-1-piperazinyl]ethyl]-1-(1-methylethyl)-1H-naphth[1,2-d]-imidazole 

Relevant articles and documents

Anti-hypertensives: 1-alkyl-2-arylpiperazinoethyl-1H-naphthimidazoles

L 15848 (8b citrate) is a new anti-hypertensive agent belonging to the class of 1-alkyl-2-aminoethylnaphthimidazoles.It lowers blood pressure in spontaneously hypertensive rats (50 mg/kg, p.o.) and in conscious normotensive and renal hypertensive d