80460-73-7 Usage
Description
4-Aminophenylboronic acid hydrochloride is an organic compound with the chemical formula C6H7BNO2·HCl. It is a white crystalline solid that is soluble in water and has a molecular weight of 157.39 g/mol. 4-AMINOPHENYLBORONIC ACID HYDROCHLORIDE is a derivative of boronic acid and contains an amino group attached to a phenyl ring. It is commonly used as a reagent in organic synthesis and as a building block for the preparation of various functional materials.
Uses
Used in Chemical Synthesis:
4-Aminophenylboronic acid hydrochloride is used as a reagent in various chemical reactions, such as the Suzuki reaction, a widely used cross-coupling reaction for the formation of carbon-carbon bonds. It can be employed to synthesize a range of organic compounds, including biaryls, which are important structural motifs in pharmaceuticals, agrochemicals, and materials science.
Used in Sensor Technology:
4-Aminophenylboronic acid hydrochloride is used as a precursor to prepare modified reduced graphene composite materials, which serve as sugar sensors for detecting analytes in fruit juice. The boronic acid moiety in the compound forms reversible covalent bonds with diols, such as sugars, enabling selective and sensitive detection of these analytes.
Used in Electrochemistry:
4-AMINOPHENYLBORONIC ACID HYDROCHLORIDE can be used to modify carbon electrodes by adsorbing aminophenol, which is then employed for the detection of NADH (nicotinamide adenine dinucleotide) and H2O2 (hydrogen peroxide). The modified electrode exhibits enhanced electrocatalytic activity and selectivity towards these analytes, making it suitable for applications in bioelectrochemistry and biosensing.
Used in Carbon Dot Synthesis:
4-Aminophenylboronic acid hydrochloride is also used in the synthesis of boron, nitrogen, and sulfur-doped carbon dots, which are a type of carbon-based nanomaterial with unique optical and electronic properties. These doped carbon dots can be employed as sensors for the detection of ascorbic acid, an important antioxidant and reducing agent, in various samples, including food and pharmaceutical products.
Check Digit Verification of cas no
The CAS Registry Mumber 80460-73-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,4,6 and 0 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 80460-73:
(7*8)+(6*0)+(5*4)+(4*6)+(3*0)+(2*7)+(1*3)=117
117 % 10 = 7
So 80460-73-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H8BNO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4,9-10H,8H2
80460-73-7Relevant articles and documents
Virtues of Volatility: A Facile Transesterification Approach to Boronic Acids
Hinkes, Stefan P.A.,Klein, Christian D.P.
supporting information, p. 3048 - 3052 (2019/05/10)
Boronic acids are an increasingly important compound class for many applications, including C-C bond formation reactions, medicinal chemistry, and diagnostics. The deprotection of boronic ester intermediates is frequently a problematic and inefficient step in boronic acid syntheses. We describe an approach that highly facilitates this transformation by leveraging the volatility of methylboronic acid and its diol esters. The method is performed under mild conditions, provides high yields, and eliminates cumbersome and problematic purification steps.
