8049-97-6

Basic information

• Product Name: MELANIN
• Synonyms: trimeric cyanamide;C05606;MELANIN;melanin from sepia officinalis;melanin synthetic cell culture tested;Melanins;POLYDIHYDROXYINDOLE;MELANIN SYNTHETIC
• CAS NO: 8049-97-6
• Molecular Formula: C18H10N2O4
• Molecular Weight: 318.283
• EINECS: 232-473-6
• Product Categories: Colours, Dyes, Indicators & Pigments;Catecholamine;Cofactor;Metabolites and Cofactors on the Metabolic Pathways Chart;M;Stains and Dyes;Stains&Dyes, A to;Cell Culture;Miscellaneous Reagents and Supplements;Reagents and Supplements
• Mol File: 8049-97-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 500.5°C at 760 mmHg
• Flash Point: 195.4°C
• Appearance: /
• Density: 1.65g/cm³
• Vapor Pressure: 3.78E-10mmHg at 25°C
• Refractive Index: 1.771
• Storage Temp.: −20°C
• CAS DataBase Reference: MELANIN(CAS DataBase Reference)
• NIST Chemistry Reference: MELANIN(8049-97-6)
• EPA Substance Registry System: MELANIN(8049-97-6)

Safety Data

• WGK Germany: 1
• Hazardous Substances Data: 8049-97-6(Hazardous Substances Data)

Usage

Description

Melanin is a nitrogenous indolic polymer that exists in various forms such as eumelanins, allomelanins, and pheomelanins. It is known for its photoprotective properties, as it can absorb radiations from the electromagnetic spectrum, making it effective against UV radiation, chemical stress, and high temperatures. Melanin can be naturally extracted from sources like cuttlefish ink or produced synthetically. It is biosynthesized by several microorganisms, including Magnoporthe grisea, Cryptococcus neoformans, Paracoccidioides brasiliensis, Vibrio cholera, Aspergillus fumigates, Alteromonas nigrifaciens, and Streptomyces sp.

Uses

Used in Cosmetics:
Melanin is used as a photoprotective agent in cosmetics for its ability to absorb UV radiation and provide protection against harmful effects on the skin.
Used in Eyeglasses:
In the eyeglasses industry, melanin is used as a component in lenses to provide protection against UV radiation, helping to shield the eyes from potential damage.
Used in Pharmaceutical Products:
Melanin is utilized in pharmaceutical products due to its photoprotective and free-radical scavenging properties, which can be beneficial in various applications, such as sunscreens.
Used in Sunscreens:
Melanin is used as a sunscreen ingredient, offering better UVA protection and requiring lower usage concentrations than other available sunscreens. Research supports its safety, as studies with radioactive melanin showed no penetration through human skin.
Used as a Free-Radical Scavenger:
A water-soluble form of melanin is available and can be formulated into products as a free-radical scavenger, helping to neutralize harmful free radicals and protect the skin and other tissues from oxidative damage.

InChI:InChI=1/C18H10N2O4/c1-5-13-9-7(3-19-13)12-10-8(11(9)17(23)15(5)21)4-20-14(10)6(2)16(22)18(12)24/h3-4,19-20H,1-2H3