807363-10-6

Basic information

• Product Name: S-(+)-Arundic Acid
• Synonyms: S-(+)-Arundic Acid;(2S)-2-Propyloctanoic Acid;(S)-(+)-2-Propyloctanoic Acid
• CAS NO: 807363-10-6
• Molecular Formula: C₁₁H₂₂O₂
• Molecular Weight: 186.29118
• Product Categories: Aliphatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 807363-10-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Ethanol
• CAS DataBase Reference: S-(+)-Arundic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: S-(+)-Arundic Acid(807363-10-6)
• EPA Substance Registry System: S-(+)-Arundic Acid(807363-10-6)

Safety Data

• Hazardous Substances Data: 807363-10-6(Hazardous Substances Data)

Usage

Uses

The S-enantiomer of Arundic Acid. An astrocyte modulating agent, in acute ischemic stroke.

Upstream product

• 1087312-91-1 (1R)-2-endo-[(2S)-propyloctanoyl]-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol 

Relevant articles and documents

A concise and efficient route to the Alzheimer's therapeutic agent (R)-arundic acid

A short and efficient procedure for the preparation of (R)-arundic acid, a therapeutic agent for the treatment of Alzheimer's disease, has been developed. Based on cheap and commercially available (1R)-(+)-camphor as the source of chiral information, (R)-arundic acid is synthesized in a four-step cyclic sequence with 55% overall yield and high optical purity, ≥98% ee. Alkyl halide and acetylene constitute the only consumable carbon sources of this method, which allows obtaining of both enantiomers and recycling of chiral auxiliary.