80768-55-4

Basic information

• Product Name: 1-Trifluoromethyl-1-cyclohexanol
• Synonyms: 1-Trifluoromethyl-1-cyclohexanol
• CAS NO: 80768-55-4
• Molecular Formula: C₇H₁₁F₃O
• Molecular Weight: 168.1568496
• Mol File: 80768-55-4.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Trifluoromethyl-1-cyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Trifluoromethyl-1-cyclohexanol(80768-55-4)
• EPA Substance Registry System: 1-Trifluoromethyl-1-cyclohexanol(80768-55-4)

Safety Data

• Hazardous Substances Data: 80768-55-4(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Odor

Minty

Uses

Intermediate in the synthesis of pharmaceuticals and agrochemicals, solvent and reagent in organic synthesis

Hazards

Harmful if swallowed or inhaled, may cause skin and eye irritation upon contact

Flammability

Flammable

Handling and storage

Handle with caution, store in a well-ventilated area away from sources of ignition.

Upstream product

• 75-63-8 Bromotrifluoromethane 
• 108-94-1 cyclohexanone 
• 2314-97-8 iodotrifluoromethane 
• 334-99-6 trifluoronitrosomethane 
• 950510-09-5 trimethyl((1-(trifluoromethyl)cyclohexyl)oxy)silane 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 2923-18-4 sodium 2,2,2-trifluoroacetate 
• 75-46-7 trifluoromethan 

Downstream Products

• 454-55-7 1-(trifluoromethyl)-1-cyclohexene 
• 401-75-2 trifluoromethylcyclohexane 

Relevant articles and documents

TRPA1 ANTAGONISTS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH PAIN AND INFLAMMATION

The present invention is directed to compounds of general formula (I) as described and defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions comprising said compounds,

Sodium trifluoroacetate: An efficient precursor for the trifluoromethylation of aldehydes

In a convenient and efficient procedure, the nucleophilic trifluoromethylation of aldehydes with sodium trifluoroacetate was achieved, using copper(I) halides as the catalyst.

Microreactors for the synthesis of fluorinated materials

The utility of microreactor for the synthesis of α-fluoro-α, β-unsaturated esters, trifluoromethylation and Michael addition reaction, is described.