808144-32-3

Basic information

• Product Name: (2,3-difluorophenyl)acetyl chloride
• Synonyms: (2,3-difluorophenyl)acetyl chloride
• CAS NO: 808144-32-3
• Molecular Weight: 190.577
• Mol File: 808144-32-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2,3-difluorophenyl)acetyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: (2,3-difluorophenyl)acetyl chloride(808144-32-3)
• EPA Substance Registry System: (2,3-difluorophenyl)acetyl chloride(808144-32-3)

Safety Data

• Hazardous Substances Data: 808144-32-3(Hazardous Substances Data)

Usage

Description

(2,3-difluorophenyl)acetyl chloride is a chemical compound with the molecular formula C8H6ClF2O. It is an acetyl chloride derivative with two fluorine atoms attached to the phenyl ring at positions 2 and 3. (2,3-difluorophenyl)acetyl chloride is known for its high reactivity and versatility, making it a valuable building block in the synthesis of various pharmaceuticals, agrochemicals, and other fine chemicals.

Uses

Used in Pharmaceutical Industry:
(2,3-difluorophenyl)acetyl chloride is used as a key intermediate in the synthesis of pharmaceuticals for its ability to undergo various chemical transformations, such as nucleophilic substitution, Friedel-Crafts acylation, and esterification reactions. Its unique structure and reactivity contribute to the development of new and effective drug molecules.
Used in Agrochemical Industry:
In the agrochemical industry, (2,3-difluorophenyl)acetyl chloride is utilized as a starting material for the production of various agrochemicals. Its reactivity allows for the creation of compounds with specific properties, such as pest control agents and herbicides, which are essential for maintaining agricultural productivity.
Used in Fine Chemicals Industry:
(2,3-difluorophenyl)acetyl chloride is also employed in the synthesis of fine chemicals, which are high-purity chemicals used in various applications, including research, specialty manufacturing, and high-value consumer products. Its versatility and reactivity make it a valuable component in the development of these specialized compounds.
Safety Precautions:
Due to the high reactivity and potential hazards of (2,3-difluorophenyl)acetyl chloride, it is crucial to handle and use this compound with proper safety measures. It should be used in a well-ventilated laboratory setting, and appropriate personal protective equipment (PPE) should be worn to minimize exposure risks.

Upstream product

• 145689-41-4 2-(2,3-difluorophenyl)acetic acid 

Downstream Products

• 849067-60-3 2-(2,3-difluoro-phenyl)-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)-ethanone 
• 849069-12-1 1-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-(2,3-difluoro-phenyl)-ethanone 
• 1156487-41-0 7-ethoxy-1,2-difluoro-3-[1-(4-propylcyclohexyl)prop-2-ynyloxy]naphthalene 
• 1156487-24-9 8-ethoxy-5,6-difluoro-3-(4-propylcyclohexyl)-2,3-dihydro-1H-benzo[f]chromene 
• 849068-01-5 2-(2,3-difluoro-phenyl)-1-(4-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)-ethanone 
• 849069-52-9 (2,3-difluoro-phenyl)-acetic acid 3-[(2,3-difluoro-phenyl)-acetyl]-1H-pyrrolo[2,3-b]pyridin-5-yl 
• 849067-92-1 2-(2,3-difluoro-phenyl)-1-(5-dimethylaminomethyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-ethanone 
• 849067-87-4 2-(2,3-difluoro-phenyl)-1-[5-(3-dimethylamino-prop-1-ynyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-ethanone 
• 675132-40-8 7,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-one 

Relevant articles and documents

Liquid crystalline compound having high optical anisotropy and liquid crystalline composition comprising the same

A novel liquid crystalline compound having a negative dielectric anisotropy and a high optical anisotropy. Since the rotation viscosity and the elasticity coefficient (K11/K33) of the liquid crystalline compound are maintained at a low level, the liquid c