80870-39-9Relevant articles and documents
Effect of Stereochemistry on Chirality and Gelation Properties of Supramolecular Self-Assemblies
Qin, Minggao,Zhang, Yaqian,Xing, Chao,Yang, Li,Zhao, Changli,Dou, Xiaoqiu,Feng, Chuanliang
, p. 3119 - 3129 (2021/01/20)
Although chiral nanostructures have been fabricated at various structural levels, the transfer and amplification of chirality from molecules to supramolecular self-assemblies are still puzzling, especially for heterochiral molecules. Herein, four series o
In vitro and in silico determination of glutaminyl cyclase inhibitors
Tran, Phuong-Thao,Hoang, Van-Hai,Lee, Jeewoo,Hien, Tran Thi Thu,Tung, Nguyen Thanh,Ngo, Son Tung
, p. 29619 - 29627 (2019/10/02)
Alzheimer's disease (AD) is the most common form of neurodegenerative disease currently. It is widely accepted that AD is characterized by the self-assembly of amyloid beta (Aβ) peptides. The human glutaminyl cyclase (hQC) enzyme is characterized by assoc
Low-valent titanium-catalyzed deprotection of allyl- and propargyl-carbamates to amines
Madhavan, Suchithra,Takagi, Hiromasa,Fukuda, Shunpei,Okamoto, Sentaro
, p. 2074 - 2077 (2016/04/26)
In the presence of Me3SiCl, Ti(O-i-Pr)4/Mg and CpTiCl3/Mg reagents effectively catalyzed the deprotection of allyloxycarbonyl (alloc)- and propargyloxycarbonyl (poc)-protected amines in THF at around room temperature to produce parent amines in good yields. Alloc- and poc-protected secondary amines were smoothly deprotected to parent amines by a reaction catalyzed by a Ti(O-i-Pr)4/Me3SiCl/Mg reagent. The deprotection of alloc- and poc-protected primary amines was successfully catalyzed by a CpTiCl3/Me3SiCl/Mg reagent.