80971-82-0

Basic information

• Product Name: BOC-TYR(AC)-OH
• Synonyms: BOC-TYR(AC)-OH;BOC-TYROSINE(AC)-OH;BOC-O-ACETYL-L-TYROSINE;BOC-L-TYROSINE(ACETYL);N-ALPHA-T-BUTOXYCARBONYL-O-ACETYL-L-TYROSINE;NALPHA-tert-Butoxycarbonyl-O-acetyl-L-tyrosine;Boc-L-Tyr(Ac)-OH;Boc-O-acetyl-L-tyrosine99%
• CAS NO: 80971-82-0
• Molecular Formula: C₁₆H₂₁NO₆
• Molecular Weight: 323.34
• Mol File: 80971-82-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: Store at 0-5°C
• CAS DataBase Reference: BOC-TYR(AC)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-TYR(AC)-OH(80971-82-0)
• EPA Substance Registry System: BOC-TYR(AC)-OH(80971-82-0)

Safety Data

• Hazardous Substances Data: 80971-82-0(Hazardous Substances Data)

Usage

General Description

BOC-TYR(AC)-OH is a chemical compound used in peptide synthesis. It consists of a protected tyrosine amino acid with an acetyl group attached to the side chain. The compound is commonly used as a building block in the solid-phase peptide synthesis process, where it is combined with other amino acids to create specific peptide sequences. The BOC (tert-butyloxycarbonyl) protecting group on the amino group and the acetyl group on the side chain serve to temporarily block reactive sites on the tyrosine molecule, allowing for controlled manipulation and subsequent deprotection during peptide assembly. BOC-TYR(AC)-OH is an important reagent for the creation of custom peptides for research, drug development, and other applications in biochemistry and molecular biology.

Upstream product

• 3978-80-1 Boc-Tyr-OH 
• 108-24-7 acetic anhydride 

Downstream Products

• 80971-83-1 1-(t-butyloxycarbonyl-O-acetyl-L-tyrosyl)aminocyclopropane-1-carbonylglycyl-L-phenylalanyl-L-leucine 2,4,6-trimethylbenzyl ester 
• 291313-44-5 (S)-N-[(S)-1-benzyl-2-hydroxyethyl]-3-(4-acetoxyphenyl)-2-[N-(tert.butoxycarbonyl)amino]propionamide 
• 210707-19-0 (S)-4-benzyl-2-[(S)-1-[N-(tert-butoxycarbonyl)amino]-2-(4-hydroxyphenyl)ethyl]-2-oxazoline 
• 291313-54-7 (S)-2-[(S)-2-(4-acetoxyphenyl)-1-[N-(tert-butoxycarbonyl)amino]ethyl]-4-benzyl-2-oxazoline 
• 80971-87-5 1-(L-tyrosyl)aminocyclopropane-1-carbonylglycyl-L-phenylalanyl-L-leucine 
• 80971-85-3 (S)-2-{(S)-2-[2-({1-[(S)-3-(4-Acetoxy-phenyl)-2-amino-propionylamino]-cyclopropanecarbonyl}-amino)-acetylamino]-3-phenyl-propionylamino}-4-methyl-pentanoic acid 
• 474070-52-5 N-butyryl-O-acetyl-L-tyrosine p-nitrophenyl ester 
• 142978-59-4 Acetic acid 4-((S)-2-{4-[3-(3-amino-propylamino)-propylamino]-butylcarbamoyl}-2-butyrylamino-ethyl)-phenyl ester 
• 1188307-55-2 Boc-Tyr(Ac)-Gly-Gly-OAll 

Relevant articles and documents

Synergistic Photobactericidal Activity Based on Ultraviolet-A Irradiation and Ferulic Acid Derivatives

Ultraviolet-A (UV-A)-mediated bactericidal activity was enhanced by combined treatment with trans-ferulic acid (trans-FA, compound 1) or its derivatives. Derivative compounds 4 and 10 contain a phenyl group or an l-tyrosine HCl tert-butyl ester, respectiv

New oxidative transformations of phenolic and indolic oxazolines: An avenue to useful azaspirocyclic building-blocks

The oxidative cyclization of a phenolic amide to a spirolactam has long been regarded as an 'impossible' reaction, because exposure of the substrates to a variety of oxidants results in formation of spirolactones with consequent loss of the amine segment. We recently communicated that this heretofore unknown transformation may be achieved by oxidation of oxazoline analogues of phenolic and indolic amides. Herein, we provide full details of our work.

Synthesis of glutamate receptor antagonist philanthotoxin-433 (PhTX-433) and its analogs

-