81-59-4

Basic information

• Product Name: 2,3-dihydro-1,4,5,8-tetrahydroxyanthraquinone
• Synonyms: 2,3-dihydro-1,4,5,8-tetrahydroxyanthraquinone;1,4,5,8-Tetrahydroxyanthraquinone, leuco derivative;Leucotetrahydroxyanthraquinone;2,3-Dihydro-1,4,5,8-tetrahydroxy-9,10-anthracenedione;5,8,9,10-tetrahydroxy-2,3-dihydroanthracene-1,4-dione;5,8,9,10-tetrahydroxy-2,3-dihydroanthracene-1,4-quinone;5,8-Dihydroxyleucoquinizarin
• CAS NO: 81-59-4
• Molecular Formula: C₁₄H₁₀O₆
• Molecular Weight: 274.2256
• EINECS: 201-364-5
• Mol File: 81-59-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 543.837 °C at 760 mmHg
• Flash Point: 296.768 °C
• Appearance: /
• Density: 1.798 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.796
• Storage Temp.: Refrigerator
• Solubility: DMSO (Very Slightly, Heated)
• PKA: 4.20±1.00(Predicted)
• CAS DataBase Reference: 2,3-dihydro-1,4,5,8-tetrahydroxyanthraquinone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dihydro-1,4,5,8-tetrahydroxyanthraquinone(81-59-4)
• EPA Substance Registry System: 2,3-dihydro-1,4,5,8-tetrahydroxyanthraquinone(81-59-4)

Safety Data

• Hazardous Substances Data: 81-59-4(Hazardous Substances Data)

Usage

Description

2,3-dihydro-1,4,5,8-tetrahydroxyanthraquinone is a chemical compound with a unique molecular structure that features a central anthraquinone ring and four hydroxyl groups attached at positions 1, 4, 5, and 8. 2,3-dihydro-1,4,5,8-tetrahydroxyanthraquinone is known for its potential applications in various fields, particularly in the pharmaceutical and chemical industries.

Uses

Used in Pharmaceutical Industry:
2,3-dihydro-1,4,5,8-tetrahydroxyanthraquinone is used as a reactant for the preparation of chloroethylaminoethylaminoanthraquinones, which exhibit potent cytotoxicity against cisplatin-resistant tumor cells. This makes it a valuable compound in the development of novel anticancer agents that can overcome drug resistance in cancer treatment.
Used in Chemical Industry:
2,3-dihydro-1,4,5,8-tetrahydroxyanthraquinone can also be utilized as an intermediate in the synthesis of various chemical compounds and dyes. Its unique structure and functional groups make it a versatile building block for creating a wide range of products with different properties and applications.

InChI:InChI=1/C14H10O6/c15-5-1-2-6(16)10-9(5)13(19)11-7(17)3-4-8(18)12(11)14(10)20/h1-2,15-18H,3-4H2

Downstream Products

• 113016-81-2 <(15)N2>-1,4-bis(phenylamino)-5,8-dihydroxy-9,10-anthraquinone 
• 52303-01-2 1,4-bis(phenylamino)-5,8-dihydroxy-9,10-anthraquinone 
• 82654-75-9 1,4-dihydroxy-5,8-bis<<2-(2-hydroxyethoxy)ethyl>amino>-9,10-antracenedione 
• 19853-97-5 1,4-Bis-(2-ethylaminoethylamino)-anthrachinon 
• 19871-57-9 1,4-bis(3-aminopropylamino)-5,8-dihydroxyanthracene-9,10-dione 
• 70788-93-1 1,4-Dihydroxy-5,8-bis-[2-(2-hydroxy-propylamino)-ethylamino]-anthraquinone 
• 70945-56-1 1,4-Bis-(2-diisopropylamino-ethylamino)-5,8-dihydroxy-anthraquinone 
• 70945-63-0 1,4-Bis-[2-(2,3-dihydroxy-propylamino)-ethylamino]-5,8-dihydroxy-anthraquinone 
• 70945-57-2 1,4-Bis-(2-dibutylamino-ethylamino)-5,8-dihydroxy-anthraquinone 
• 70945-58-3 1,4-Dihydroxy-5,8-bis-[2-(methyl-phenyl-amino)-ethylamino]-anthraquinone 
• 3179-90-6 5,8-dihydroxy-1,4-bis<<2-hydroxyethyl>amino>-9,10-anthracenedione 
• 70476-67-4 1,4-bis-{[2-(diethylamino)ethyl]amino)-5,8-dihydroxyanthracene-9,10-dione 
• 70945-67-4 5,8-dihydroxy-1,4-bis<4-(dimethylaminobutyl)amino>-9,10-anthracenedione 
• 70945-68-5 1,4-Bis-(5-dimethylamino-pentylamino)-5,8-dihydroxy-anthraquinone