81090-52-0Relevant articles and documents
Nitromethane with IBX/TBAF as a nitrosating agent: Synthesis of nitrosamines from secondary or tertiary amines under mild conditions
Potturi, Hima K.,Gurung, Ras K.,Hou, Yuqing
, p. 626 - 631 (2012/02/16)
Aliphatic or aromatic N,N-disubstituted nitrosamine was generated in fair to excellent yield from the reaction of a secondary or tertiary amine with o-iodoxybenzoic acid (IBX) or o-iodosylbenzoic acid (IBA)/R4NX (X = halide) and nitromethane. The product yield was strongly influenced by both the halide of R4NX and iodanes. IBX gave a higher yield than IBA, while the halides follow F- > Cl- > Br- ~ I-. Nitrous acid formed in situ from nitromethane and IBX (or IBA)/halides is likely responsible for the observed reaction.
REGIOSELECTIVE MONOBROMINATION OF AROMATIC AMINES WITH TETRABUTYLAMMONIUM TRIBROMIDE
Berthelot, J.,Guette, C.,Essayegh, M.,Desbene, P.L.,Basselier, J.J.
, p. 1641 - 1646 (2007/10/02)
A simple and efficient method for monobromination of aromatic amines predominantly in the para position is reported.Tetrabutylammonium tribromide is used at 20 deg C and yields of parabromoanilines are higher than 90percent.