81102-44-5 Usage
Family
Belongs to the adenosine family
Structure
Modified form of adenosine with a bromine atom at the 8th position and an amino group at the 2nd position of the adenine ring
Potency
Potent and selective agonist for the adenosine A1 receptor
Role
Regulates physiological processes including cardiac function and neurotransmitter release
Therapeutic potential
Studied for potential applications in cardiovascular diseases and neurodegenerative disorders
Target
Specifically targets the adenosine A1 receptor
Candidate
Promising candidate for the development of novel drug treatments
Check Digit Verification of cas no
The CAS Registry Mumber 81102-44-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,1,0 and 2 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 81102-44:
(7*8)+(6*1)+(5*1)+(4*0)+(3*2)+(2*4)+(1*4)=85
85 % 10 = 5
So 81102-44-5 is a valid CAS Registry Number.
81102-44-5Relevant articles and documents
Synthesis of Phosphoramidite Monomers Equipped with Complementary Bases for Solid-Phase DNA Oligomerization
Romero-Pérez, Sonia,López-Martín, Isabel,Martos-Maldonado, Manuel C.,Somoza, álvaro,González-Rodríguez, David
supporting information, p. 41 - 45 (2020/01/03)
We describe the preparation of two monomers that bear complementary nucleobases at the edges (guanine-2′-deoxycytidine and 2-aminoadenine-2′-deoxyuridine) and that are conveniently protected and activated for solid-phase automated DNA synthesis. We report the optimized synthetic routes leading to the four nucleobase derivatives involved, their cross-coupling reactions into dinucleobase-containing monomers, and their oligomerization in the DNA synthesizer.
Synthesis and properties of 2,6-diamino-8,2'-anhydro-8-mercapto-9-β-D-arabinofuranosylpurine
Muraoka
, p. 3449 - 3454 (2007/10/02)
-
