81280-21-9

Basic information

• Product Name: C₂₁H₁₉NO₃
• Synonyms: C₂₁H₁₉NO₃
• CAS NO: 81280-21-9
• Molecular Weight: 333.387
• Mol File: 81280-21-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₂₁H₁₉NO₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₁₉NO₃(81280-21-9)
• EPA Substance Registry System: C₂₁H₁₉NO₃(81280-21-9)

Safety Data

• Hazardous Substances Data: 81280-21-9(Hazardous Substances Data)

Upstream product

• 88214-29-3 C₁₅H₁₄O₄ 
• 941-69-5 N-phenyl-maleimide 
• 76051-89-3 3-methoxy-3a-methyl-3aH-indene 
• 106124-72-5 bistrichloroethyl 2,2a,7a,7b-tetrahydro-2a-methoxy-7b-methyl-1H-cyclopentindazole-1,2-dicarboxylate 

Downstream Products

• 106124-76-9 2,2a,7a,7b-tetrahydro-2a-methoxy-7b-methyl-2-toluene-p-sulphonyl-1H-cyclopentisoindol-1-one 
• 81280-24-2 (5aS,5bR,8aR,8bS,8cR)-8b-Methoxy-8c-methyl-7-phenyl-5b,8a,8b,8c-tetrahydro-5aH-7-aza-dicyclopenta[a,cd]indene-6,8-dione 
• 81280-24-2 (5aS,5bS,8aS,8bS,8cR)-8b-Methoxy-8c-methyl-7-phenyl-5b,8a,8b,8c-tetrahydro-5aH-7-aza-dicyclopenta[a,cd]indene-6,8-dione 
• 941-69-5 N-phenyl-maleimide 
• 75950-76-4 1-methoxy-1-methyl-1H-indene 

Relevant articles and documents

3aH-Indenes. Part 6. Cycloaddition of 3-Methoxy- and 3-Trimethylsiloxy-3a-methyl-3aH-indenes to Heterodienophiles; Approaches to Azaannulenes

3-Methoxy-3a-methyl-3aH-indene (4a) reacts with dimethyl azodicarboxylate and with bistrichloroethyl azodicarboxylate to give the -cycloadducts (5a) and (5c), respectively. 3- trimethylsiloxy-3a-methyl-3aH-indene (4b) reacts similarly with the same

Generation of 3-Methoxy-3a-methyl-3aH-indene and Study of its Cycloaddition Reactions

The title compound (1) has been prepared from indan-1-one by Birch reduction and methylation followed by the introduction of a further double bond, enolisation of the ketone, and O-methylation.The tetraenol ether (1) is the first 3aH-indene derivative to be isolated.It is shown to be oxidised by air to the Z-cinnamic ester (5), and to undergo ready rearrangement to the 1H-indene (7).Cycloadditions of N-phenyltriazolinedione, diethyl azodiformate, and dimethyl acetylenedicarboxylate to the termini of the tetraene are observed.These formal cycloadditions are in contrast to the addition which is observed with N-phenylmaleimide.The adduct rearranges on heating to give a mixture of adducts: it is suggested that this process involves dissociation of the adduct into its components and their re-combination.