813452-18-5 Usage
Description
(S)-1-((2S,3S,11bS)-2-amino-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-3-yl)-4-(fluoromethyl)pyrrolidin-2-one is a complex organic molecule characterized by a pyrrolidinone ring structure. It features an amino group and a fluoromethyl group, along with multiple methoxy substituents. The molecule also includes a hexahydro-1H-pyrido[2,1-a]isoquinolin-3-yl moiety, which contributes to its intricate and unique structure. The presence of the amino and fluoromethyl groups, along with its complex structure, suggests potential pharmacological or biological activity, possibly allowing for specific interactions with biological targets.
Uses
Used in Pharmaceutical Industry:
(S)-1-((2S,3S,11bS)-2-amino-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-3-yl)-4-(fluoromethyl)pyrrolidin-2-one is used as a potential pharmaceutical compound for its likely pharmacological or biological activity. The presence of the amino group and fluoromethyl group, along with its complex structure, may enable it to interact with specific biological targets, making it a candidate for the development of new drugs.
Used in Chemical Research:
In the field of chemical research, (S)-1-((2S,3S,11bS)-2-amino-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-3-yl)-4-(fluoromethyl)pyrrolidin-2-one can be used as a subject of study to understand its chemical properties, reactivity, and potential applications in the synthesis of other complex molecules.
Used in Material Science:
The unique structure of (S)-1-((2S,3S,11bS)-2-amino-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-3-yl)-4-(fluoromethyl)pyrrolidin-2-one may also find applications in material science, where its properties could be harnessed for the development of new materials with specific characteristics, such as improved stability or reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 813452-18-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,1,3,4,5 and 2 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 813452-18:
(8*8)+(7*1)+(6*3)+(5*4)+(4*5)+(3*2)+(2*1)+(1*8)=145
145 % 10 = 5
So 813452-18-5 is a valid CAS Registry Number.
813452-18-5Relevant articles and documents
Discovery of carmegliptin: A potent and long-acting dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Mattei, Patrizio,Boehringer, Markus,Di Giorgio, Patrick,Fischer, Holger,Hennig, Michael,Huwyler, Joerg,Kocer, Buelent,Kuhn, Bernd,Loeffler, Bernd M.,MacDonald, Alexander,Narquizian, Robert,Rauber, Etienne,Sebokova, Elena,Sprecher, Urs
, p. 1109 - 1113 (2010)
Design, synthesis, and SAR are described for a class of DPP-IV inhibitors based on aminobenzo[a]quinolizines with non-aromatic substituents in the S1 specificity pocket. One representative thereof, carmegliptin (8p), was chosen for clinical development. Its X-ray structure in complex with the enzyme and early efficacy data in animal models of type 2 diabetes are also presented.
