81357-18-8

Basic information

• Product Name: 4-Oxo-1,2-piperidinedicarboxylic acid 1-(tert-butyl) 2-methyl ester
• Synonyms: 4-Oxo-1,2-piperidinedicarboxylic acid 1-(tert-butyl) 2-methyl ester;1-tert-butyl 2-methyl 4-oxopiperidine-1,2-dicarboxylate;Methyl 1-Boc-4-oxopiperidine-2-carboxylate;Methyl N-Boc-4-Oxo-piperidine-2-carboxylate;1,2-Piperidinedicarboxylicacid, 4-oxo-, 1-(1,1-diMethylethyl) 2-Methyl ester;1-Boc-4-oxo-piperidine-2-carboxylic acid methyl ester
• CAS NO: 81357-18-8
• Molecular Formula: C₁₂H₁₉NO₅
• Molecular Weight: 257.28
• Product Categories: Heterocycles;Heterocycle-other series
• Mol File: 81357-18-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 350.011 ºC at 760 mmHg
• Flash Point: 165.481 ºC
• Appearance: /
• Density: 1.175
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.483
• Storage Temp.: 2-8°C
• PKA: -3.59±0.40(Predicted)
• CAS DataBase Reference: 4-Oxo-1,2-piperidinedicarboxylic acid 1-(tert-butyl) 2-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Oxo-1,2-piperidinedicarboxylic acid 1-(tert-butyl) 2-methyl ester(81357-18-8)
• EPA Substance Registry System: 4-Oxo-1,2-piperidinedicarboxylic acid 1-(tert-butyl) 2-methyl ester(81357-18-8)

Safety Data

• Hazardous Substances Data: 81357-18-8(Hazardous Substances Data)

Usage

General Description

4-Oxo-1,2-piperidinedicarboxylic acid 1-(tert-butyl) 2-methyl ester, also known as t-Boc-2-methylpiperidine-4-carboxylic acid, is a chemical compound with the molecular formula C13H23NO4. It is a white to off-white solid that is soluble in organic solvents such as methanol and dichloromethane. 4-Oxo-1,2-piperidinedicarboxylic acid 1-(tert-butyl) 2-methyl ester is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals, as well as in the production of peptides. It is also utilized as a reagent for the protection of amines in organic synthesis. Additionally, it has potential applications in the fields of molecular biology and medicinal chemistry. Overall, 4-Oxo-1,2-piperidinedicarboxylic acid 1-(tert-butyl) 2-methyl ester is a versatile chemical with a wide range of uses in various industries.

InChI:InChI=1/C12H19NO5/c1-12(2,3)18-11(16)13-6-5-8(14)7-9(13)10(15)17-4/h9H,5-7H2,1-4H3

Upstream product

• 38053-91-7 2-trimethylsilyloxy-1,3-butadiene 
• 81357-15-5 [(E)-tert-Butoxycarbonylimino]-acetic acid methyl ester 
• 68014-21-1 triphenyl(t-butoxycarbonylimino)phosphorane 
• 187753-13-5 N-tert-butoxycarbonyl-cis-4-hydroxy-L-pipecolinic acid methyl ester 
• 144913-66-6 4-hydroxy-2-piperidine carboxylic acid methyl ester 

Downstream Products

• 181269-87-4 1-tert-butyl 2-methyl cis-4-hydroxypiperidine-1,2-dicarboxylate 
• 844504-87-6 N-Boc-4-hydroxy-4-allylproline methyl ester 
• 187753-15-7 methyl 4-oxopiperidine-2-carboxylate 
• 1259011-96-5 (±)-methyl 1-benzyloxycarbonyl-4,4-difluoropiperidine-2-carboxylate 

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