81516-60-1

Basic information

• Product Name: Quinoxaline, 2-propyl- (9CI)
• Synonyms: Quinoxaline, 2-propyl- (9CI)
• CAS NO: 81516-60-1
• Molecular Formula: C₁₁H₁₂N₂
• Molecular Weight: 172.22638
• Product Categories: QUINOXALINE
• Mol File: 81516-60-1.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Quinoxaline, 2-propyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoxaline, 2-propyl- (9CI)(81516-60-1)
• EPA Substance Registry System: Quinoxaline, 2-propyl- (9CI)(81516-60-1)

Safety Data

• Hazardous Substances Data: 81516-60-1(Hazardous Substances Data)

Upstream product

• 81516-59-8 ethyl 11-methyl-10,13-dioxohexadec-11-enoate 
• 95-54-5 1,2-diamino-benzene 
• 88297-83-0 1-chloro-1-benzamido-2-pentanone 
• 1448-87-9 2-chloroquinoxaline 
• 927-77-5 n-propylmagnesium bromide 
• 5343-92-0 1,2-pentanediol 
• 528-29-0 1,2-Dinitrobenzene 
• 91-19-0 2,3-diethynylquinoxaline 
• 123-72-8 butyraldehyde 
• 91838-74-3 2-ethenylquinoxaline 
• 13061-96-6 dihydroxy-methyl-borane 
• 88-74-4 2-nitro-aniline 
• 621-77-2 tripentylamine 

Downstream Products

• 110038-75-0 2-propyltetrahydroquinoxaline 

Relevant articles and documents

Method for synthesizing quinoxaline compound under visible light induced iron catalysis condition

The invention belongs to the technical field of compound synthesis, and particularly relates to a method for synthesizing quinoxaline compounds under visible light induced iron catalysis conditions. The method comprises the following steps: by taking non-activated aliphatic amine and o-phenylenediamine as raw materials, under the action of a photosensitizer, under the illumination of visible light, reacting in a solvent at room temperature and under oxygen conditions to generate the quinoxaline compound. The method has better substrate universality and relatively mild reaction conditions, not only realizes synthesis of the quinoxaline compound for the first time, but also widens the field of organic synthesis.

Nickel(ii)-catalyzed addition of aryl-, alkenyl-, and alkylboronic acids to alkenylazaarenes

A nickel(II)-catalyzed addition of aryl-, alkenyl-, and alkylboronic acids to alkenylazaarenes was presented. This reaction exhibited high efficiency (up to 93% yield), a broad substrate scope (seven types of heterocycles), and good functional group compatibility. The resulting products can be further transformed to many useful building blocks. Finally, the preliminary studies suggested that the adjacent N atom of the heterocycles was essential for the high reactivity.

Radical C?H Acylation of Nitrogen Heterocycles Induced by an Aerobic Oxidation of Aldehydes

An aerobic radical approach for the synthesis of unsymmetrical heteroaryl ketones is described herein. The reaction involves cross-dehydrogenative coupling between aldehydes and heteroaromatic bases with molecular oxygen (O2). The key aspect of the method is the generation of reactive acyl radical via homolytic activation of aldehyde C?H bond using O2 as the sole oxidant. The reaction has a good substrate scope with respect to aldehydes and functionalized nitrogen heterocycles. Based on our mechanistic studies, a radical chain pathway is suggested for the reaction. A synthetic application of the method is demonstrated in the formal synthesis of natural alkaloid (±) angustureine.