81561-77-5

Basic information

• Product Name: 4-T-BUTYL PROPIOPHONE
• Synonyms: 4-T-BUTYL PROPIOPHONE;2-Propanone, 1-[4-(1,1-diMethylethyl)phenyl]-;1-(4-tert-butylphenyl)propan-2-one
• CAS NO: 81561-77-5
• Molecular Formula: C₁₃H₁₈O
• Molecular Weight: 190.28142
• Mol File: 81561-77-5.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 263.5±9.0 °C(Predicted)
• Appearance: /
• Density: 0.939±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 4-T-BUTYL PROPIOPHONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-T-BUTYL PROPIOPHONE(81561-77-5)
• EPA Substance Registry System: 4-T-BUTYL PROPIOPHONE(81561-77-5)

Safety Data

• Hazardous Substances Data: 81561-77-5(Hazardous Substances Data)

Usage

General Description

4-T-BUTYL PROPIOPHONE, also known as p-tert-butylpropiophenone, is a chemical compound with the molecular formula C13H18O. It is a colorless liquid with a sweet odor, and it is commonly used as a fragrance ingredient in perfumes and other cosmetic products. This chemical is also used as a flavoring agent in food products and as a precursor in the synthesis of various pharmaceuticals. Additionally, 4-T-BUTYL PROPIOPHONE is used in the production of polymer resins and as a solvent in several industrial processes. However, it is important to handle this compound with care, as it is considered to be a hazardous substance and may cause skin and eye irritation, as well as respiratory issues if inhaled.

Upstream product

• 140244-80-0 (Z)-(4-tert-butylphenyl)azo tert-butyl sulfide 
• 67-64-1 acetone 
• 253185-03-4 tert-butylbenzene 
• 852815-78-2 2-(4-tert-butylphenyl)-N-methoxy-N-methylacetamide 
• 7598-28-9 4-tert-butylphenyltosylate 
• 3972-56-3 4-(tert-butyl)chlorobenzene 
• 22796-14-1 1-(tert-butyl)-4-(methylsulfonyl)benzene 
• 3549-23-3 methyl 2-(4-tert-butylphenyl)acetate 
• 75-16-1 methylmagnesium bromide 
• 32857-63-9 4-t-butylphenylacetic acid 
• 108-24-7 acetic anhydride 
• 68175-34-8 1-(tert-butyl)-4-(prop-1-en-1-yl)benzene 
• 58567-80-9 1-(tert-butyl)-4-propylbenzene 
• 80-54-6 lilial 

Downstream Products

• 852815-79-3 ethyl 5-[4-(1,1-dimethylethyl)phenyl]-2,4-dioxopentanoate 

Relevant articles and documents

Cobalt-Catalyzed Aerobic Oxidative Cleavage of Alkyl Aldehydes: Synthesis of Ketones, Esters, Amides, and α-Ketoamides

A widely applicable approach was developed to synthesize ketones, esters, amides via the oxidative C?C bond cleavage of readily available alkyl aldehydes. Green and abundant molecular oxygen (O2) was used as the oxidant, and base metals (cobalt and copper) were used as the catalysts. This strategy can be extended to the one-pot synthesis of ketones from primary alcohols and α-ketoamides from aldehydes.

Anti-Markovnikov Oxidation of β-Alkyl Styrenes with H2O as the Terminal Oxidant

Oxygenation of alkenes is one of the most straightforward routes for the construction of carbonyl compounds. Wacker oxidation provides a broadly useful strategy to convert the mineral oil into higher value-added carbonyl chemicals. However, the conventional Wacker chemistry remains problematic, such as the poor activity for internal alkenes, the lack of anti-Markovnikov regioselectivity, and the high cost and chemical waste resulted from noble metal catalysts and stoichiometric oxidant. Here, we describe an unprecedented dehydrogenative oxygenation of β-alkyl styrenes and their derivatives with water under external-oxidant-free conditions by utilizing the synergistic effect of photocatalysis and proton-reduction catalysis that can address these challenges. This dual catalytic system possesses the single anti-Markovnikov selectivity due to the property of the visible-light-induced alkene radical cation intermediate.

NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND

There are provided compounds represented by the following general formula (I) or pharmaceutically acceptable salts of thereof, which have a superior monoacylglycerol acyltransferase 2 inhibitory action: wherein Ring A represents a partially saturated heteroaryl group, an aryl group or a heteroaryl group, RB represents a C4-18 alkyl group, a C3-8 cycloalkyl group, a partially saturated aryl group, an aryl group, or the following formula (II): wherein V represents the formula -CR11R12-, -CO-, -CO-O-, or -CO-NH-, W represents a single bond or a C1-3 alkylene group, and Ring B represents a C3-8 cycloalkyl group, a C3-8 cycloalkenyl group, a partially saturated heteroaryl group, a saturated heterocyclyl group, an aryl group, or a heteroaryl group, Y represents a nitrogen atom or the formula N+(RF), RF represents a C1-4 alkyl group, and m and n, which may be the same or different, each represent an integer of 0 or 1.