817621-48-0

Basic information

• Product Name: 4-(2-chloro-6-fluorophenylamino)benzonitrile
• Synonyms: 4-(2-chloro-6-fluorophenylamino)benzonitrile
• CAS NO: 817621-48-0
• Molecular Weight: 246.671
• Mol File: 817621-48-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(2-chloro-6-fluorophenylamino)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-chloro-6-fluorophenylamino)benzonitrile(817621-48-0)
• EPA Substance Registry System: 4-(2-chloro-6-fluorophenylamino)benzonitrile(817621-48-0)

Safety Data

• Hazardous Substances Data: 817621-48-0(Hazardous Substances Data)

Upstream product

• 623-03-0 4-Cyanochlorobenzene 
• 363-51-9 2-chloro-6-fluoroaniline 

Downstream Products

• 332903-78-3 2-chloro-N-(2-chloro-6-fluoro-phenyl)-N-p-tolylacetamide 
• 220991-20-8 lumiracoxib 

Relevant articles and documents

Synthesis of new N-aryl oxindoles as intermediates for pharmacologically active compounds

Various new N-aryl oxindoles were synthesized as intermediates for the preparation of pharmacologically active 2-(N-arylamino)-phenylacetic acids. Two novel approaches were explored for the construction of diarylamine and N-aryl oxindole core structures, in addition to Buchwald-arylamination and Smiles rearrangement. Condensation of anilines with 2-oxo-cyclohexylidene-acetic acid derivatives and subsequent dehydrogenation is a new and viable method for the preparation of N-aryl oxindoles. Graphical Abstract.