81806-30-6

Basic information

• Product Name: Boc-Phe-εAhx-OMe
• Synonyms: Boc-Phe-εAhx-OMe
• CAS NO: 81806-30-6
• Molecular Weight: 392.495
• Mol File: 81806-30-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Boc-Phe-εAhx-OMe(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-Phe-εAhx-OMe(81806-30-6)
• EPA Substance Registry System: Boc-Phe-εAhx-OMe(81806-30-6)

Safety Data

• Hazardous Substances Data: 81806-30-6(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 128372-97-4 N-tert-butoxycarbonyl-6-aminohexanoic acid methyl ester 
• 6404-29-1 6-(tert-butoxycarbonylamino)hexanoic acid 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 1926-80-3 methyl 6-aminocaproate hydrochloride 

Downstream Products

• 130532-52-4 (S)-6-(2-(tert-butoxycarbonylamino)-3-phenyl-propanamido)hexanoic acid 
• 138199-85-6 Z-iPrTyr-D-Met-Gly-Phe-εAhx-OMe 
• 138199-87-8 H-iPrTyr-D-Met-Gly-Phe-εAhx-OH 
• 138199-86-7 H-PrTyr-D-Met-Gly-Phe-εAhx-OH 
• 81806-37-3 6-[(S)-2-(2-Amino-acetylamino)-3-phenyl-propionylamino]-hexanoic acid methyl ester; hydrochloride 
• 81806-35-1 Boc-Gly-Phe-εAhx-OMe 
• 138199-84-5 Z-PrTyr-D-Met-Gly-Phe-εAhx-OMe 

Relevant articles and documents

Direct Catalytic Alcoholysis of Unactivated 8-Aminoquinoline Amides

Direct catalytic alcoholysis of unactivated amides is one of the most difficult challenges in organic chemistry, and an applicable method for cleaving amides used as directing groups in regioselective functionalization reactions has not been reported. Herein, we report direct catalytic alcoholysis of 8-aminoquinoline amides, which are highly effective directing groups in regioselective functionalization reactions. The reactions proceeded with a simple combination of substrates, air-stable catalysts, and alcohols, affording the corresponding esters in good yields with broad functional group tolerance. Highly chemoselective cleavage of the 8-aminoquinoline amides in the presence of related carbonyl functionalities and preliminary mechanistic studies are also described.

SYNTHESIS OF ENKEPHALIN ANALOGS. PART IV. N-ALKYLATED DERIVATIVES

Four new derivatives of enkephalin analogs: H-PrTyr-D-Met-Gly-Phe-εAhx-εAhx-OH (24).H-iPrTyr-D-Met-Gly-Phe-εAhx-εAhx-Oh (25).H-Pr-Tyr-D-Met-Gly-Phe-εAhx-OH (30) and H-iPrTyr-D-Met-Gly-Phe-εAhx-OH (31) have been synthesized and tested for agonistic, antagonistic and analgesic activity.Compound 24 showed a moderate μ agonistic potency and high selectivity.