82090-52-6

Basic information

• Product Name: IMIDAZO[1,2-A]PYRIDIN-2-YLMETHANOL
• Synonyms: IMIDAZO[1,2-A]PYRIDIN-2-YLMETHANOL;2-(HYDROXYMETHYL)IMIDAZO[1,2-A]PYRIDINE;IMIDAZO[1,2-A]PYRIDINE-2-METHANOL;2-(Hydroxymethyl)imidazo[1,2-a]pyridine 90%;2-(Hydroxymethyl)imidazo[1,2-a]pyridine90%;(H-Imidazo[1,2-a]pyridin-2-yl)methanol
• CAS NO: 82090-52-6
• Molecular Formula: C₈H₈N₂O
• Molecular Weight: 148.16
• Product Categories: Hydroxymethyl's;Fused Ring Systems
• Mol File: 82090-52-6.mol
• Article Data: 12

Chemical Properties

• Melting Point: 101.5-103.5
• Appearance: /
• Density: 1.267 g/cm³
• Refractive Index: 1.641
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: IMIDAZO[1,2-A]PYRIDIN-2-YLMETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: IMIDAZO[1,2-A]PYRIDIN-2-YLMETHANOL(82090-52-6)
• EPA Substance Registry System: IMIDAZO[1,2-A]PYRIDIN-2-YLMETHANOL(82090-52-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 22-26-36/37/39
• Hazardous Substances Data: 82090-52-6(Hazardous Substances Data)

Usage

General Description

IMIDAZO[1,2-A]PYRIDIN-2-YLMETHANOL is a chemical compound with the molecular formula C9H8N2O. It is a heterocyclic organic compound that contains both imidazole and pyridine rings in its structure. It is commonly used as a building block in the synthesis of pharmaceuticals and other organic compounds. IMIDAZO[1,2-A]PYRIDIN-2-YLMETHANOL is also known for its potential use in medicinal chemistry and drug development due to its diverse chemical properties and biological activities. Additionally, it is used as a reagent in chemical reactions and research studies in the field of organic chemistry.

InChI:InChI=1/C8H8N2O/c11-6-7-5-10-4-2-1-3-8(10)9-7/h1-5,11H,6H2

Upstream product

• 38922-77-9 ethyl 3-imidazo[1,2-a]pyridine-2-carboxylate 
• 504-29-0 2-aminopyridine 
• 721426-33-1 C₁₀H₁₀N₂O₂ 

Downstream Products

• 118000-43-4 imidazo[1,2-a]pyridine-2-carbaldehyde 
• 857350-33-5 3-amino-2-formylimidazo[1,2-a]pyridine 
• 429690-60-8 3-nitroimidazo[1,2-a]pyridine-2-carbaldehyde 
• 118001-85-7 4-((E)-2-Imidazo[1,2-a]pyridin-2-yl-vinyl)-benzaldehyde 
• 118001-82-4 4-((E)-2-Imidazo[1,2-a]pyridin-2-yl-vinyl)-benzonitrile 
• 1196072-09-9 TH-1456 

Relevant articles and documents

METTL3 INHIBITORY COMPOUNDS

The present invention relates to compounds of formula (I) that function as inhibitors of METTL3 (N6-adenosine-methyltransferase 70 kDa subunit) enzyme activity: X-Y-Z5 (I) wherein X, Y and Z are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, and autoimmune diseases, as well as other diseases or conditions in which METTL3 activity 10 is implicated.

GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES

Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions associated with the enzyme glucosylceramide synthase (GCS).

METHYL SULFANYL PYRMIDMES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS

The present invention relates to pyrimidine derivatives of Formula (Ia) and (Ib) (including tautomers, isomers, prodrugs, and pharmaceutically acceptable salts thereof). Said compounds are useful in the treatment of pain (such as neuropathic pain), inflammation, and epilepsy (by acting as anticonvulsants). Methods of medical treatment making use of said compounds, as well as additional compounds of Formula (IIa) and (IIb), are also disclosed.