82238-92-4

Basic information

• Product Name: 1-(1-NAPHTHYL)PYRROLIDINE
• Synonyms: 1-NAPHTHALEN-1-YL-PYRROLIDINE;1-(1-NAPHTHYL)PYRROLIDINE
• CAS NO: 82238-92-4
• Molecular Formula: C₁₄H₁₅N
• Molecular Weight: 197.28
• Mol File: 82238-92-4.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 348℃
• Flash Point: 149℃
• Appearance: /
• Density: 1.107
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.642
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-(1-NAPHTHYL)PYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-NAPHTHYL)PYRROLIDINE(82238-92-4)
• EPA Substance Registry System: 1-(1-NAPHTHYL)PYRROLIDINE(82238-92-4)

Safety Data

• Hazardous Substances Data: 82238-92-4(Hazardous Substances Data)

Usage

General Description

1-(1-Naphthyl)pyrrolidine is a chemical compound with the formula C16H17N. It is formed by fusing together a naphthalene ring and a pyrrolidine ring, resulting in a distinct structure. 1-(1-Naphthyl)pyrrolidine is often used in the field of pharmaceuticals and organic chemistry, with applications in drug synthesis and research. It is known for its potential as a building block in the synthesis of various biologically active compounds. Additionally, 1-(1-Naphthyl)pyrrolidine has been studied for its potential as a chiral ligand in asymmetric catalysis and its ability to form stable complexes with transition metals. Overall, this chemical plays a significant role in the advancement of drug development and organic synthesis processes.

InChI:InChI=1/C14H15N/c1-2-8-13-12(6-1)7-5-9-14(13)15-10-3-4-11-15/h1-2,5-9H,3-4,10-11H2

Upstream product

• 109-99-9 tetrahydrofuran 
• 134-32-7 1-amino-naphthalene 
• 110-56-5 1,4-dichlorobutane 
• 201230-82-2 carbon monoxide 
• 22950-23-8 N-(2-propenyl)-1-naphthylamine 
• 110-52-1 1,4-dibromo-butane 
• 7007-34-3 1-(3,4-dihydro-1-naphthalenyl)pyrrolidine 
• 123-75-1 pyrrolidine 
• 90-11-9 1-Bromonaphthalene 
• 628-21-7 1,4-Diiodobutane 
• 90-13-1 1-Chloronaphthalene 
• 68211-49-4 1-naphthyl tosylate 
• 110-63-4 Butane-1,4-diol 
• 321-38-0 1-Fluoronaphthalene 

Relevant articles and documents

Organic photoredox catalytic α-C(sp3)-H phosphorylation of saturated: Aza -heterocycles

A metal-free C(sp3)-H phosphorylation of saturated aza-heterocycles via the merger of organic photoredox and Br?nsted acid catalyses was established under mild conditions. This protocol provided straightforward and economic access to a variety of valuable α-phosphoryl cyclic amines by using commercially available diarylphosphine oxide reagents. In addition, the D-A fluorescent molecule DCQ was used for the first time as a photocatalyst and exhibited an excellent photoredox catalytic efficiency in this transformation. A series of mechanistic experiments and DFT calculations demonstrated that this transformation underwent a sequential visible light photoredox catalytic oxidation/nucleophilic addition process.

Practical direct synthesis of: N -aryl-substituted azacycles from N -alkyl protected arylamines using TiCl4and DBU

A novel transformation of N-alkyl protected arylamines and cyclic ethers into N-aryl substituted azacycles is described. Alkyl groups have been used for the protection of amines in organic syntheses. In this synthesis, N-alkyl protected arylamines were reacted with cyclic ethers in the presence of TiCl4 and DBU, crucial reagents affording five- and six-membered azacycles. In particular, utilization of the novel TiCl4/DBU-mediated reaction allows various N-alkyl protected arylamines such as N-methyl-, N-ethyl-, N-isopropyl, and N-tert-butyl arylamines to be readily converted into N-aryl substituted azacycles in high yields. This practical approach using various N-alkyl arylamines leads to the efficient preparation of azacycles.

Visible-Light-Mediated C(sp3)–H Thiocarbonylation for Thiolactam Preparation with Potassium Sulfide

We report herein a protocol for thiolactam preparation with potassium sulfide via visible-light-mediated C(sp3)–H thiocarbonylation, in which polysulfide dianions and radical anions generated from potassium sulfide were the key active species. A variety of thiolactams were straightforward established under mild conditions. Moreover, it was successfully applied to structural modification of tetrahydroberberine.