82321-04-8 Usage
Description
N-SUCCINIMIDYL 6-(2,4-DINITROANILINO)HEXANOATE, also known as N-(2,4-Dinitrophenyl)-6-aminocaproic acid N-succinimidyl ester, is an amine-reactive DNP-X succinimidyl ester. It is a chemical compound that can be used to create bioconjugates, which are conjugates of biological molecules with other molecules or ligands. The DNP-X succinimidyl ester group allows for the covalent attachment of amines to the molecule, enabling the formation of stable bioconjugates that can be detected with anti-dinitrophenyl (anti-DNP) antibodies.
Uses
Used in Bioconjugation:
N-SUCCINIMIDYL 6-(2,4-DINITROANILINO)HEXANOATE is used as an amine-reactive DNP-X succinimidyl ester for the creation of bioconjugates. The amine-reactive group allows for the covalent attachment of amines to the molecule, enabling the formation of stable bioconjugates that can be detected with anti-dinitrophenyl (anti-DNP) antibodies.
Used in Research and Diagnostic Applications:
N-SUCCINIMIDYL 6-(2,4-DINITROANILINO)HEXANOATE is used as a reagent in research and diagnostic applications for the detection and analysis of biomolecules. The bioconjugates formed using this compound can be used in various assays, such as enzyme-linked immunosorbent assays (ELISA), fluorescence-based assays, and other immunoassays, to detect and quantify specific biomolecules.
Used in Drug Development:
N-SUCCINIMIDYL 6-(2,4-DINITROANILINO)HEXANOATE can be used in drug development for the synthesis of drug conjugates. The bioconjugation of drugs with targeting molecules, such as antibodies or peptides, can improve the drug's selectivity, efficacy, and reduce side effects by delivering the drug specifically to the target site.
Used in Biomaterials and Nanotechnology:
N-SUCCINIMIDYL 6-(2,4-DINITROANILINO)HEXANOATE can be used in the development of biomaterials and nanotechnology applications. The bioconjugation of this compound with various materials, such as nanoparticles, hydrogels, or surfaces, can enable the creation of functional materials with specific properties, such as targeted drug delivery systems, biosensors, or biocompatible coatings.
Check Digit Verification of cas no
The CAS Registry Mumber 82321-04-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,3,2 and 1 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 82321-04:
(7*8)+(6*2)+(5*3)+(4*2)+(3*1)+(2*0)+(1*4)=98
98 % 10 = 8
So 82321-04-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H18N4O8/c21-14-7-8-15(22)18(14)28-16(23)4-2-1-3-9-17-12-6-5-11(19(24)25)10-13(12)20(26)27/h5-6,10,17H,1-4,7-9H2
82321-04-8Relevant articles and documents
Surface modification of magnetic nanoparticle via Cu(I)-catalyzed alkyne-azide [2 + 3] cycloaddition
Lin, Po-Chiao,Ueng, Shau-Hua,Yu, Sheng-Chieh,Jan, Mi-Dan,Adak, Avijit Kumar,Yu, Ching-Ching,Lin, Chun-Cheng
, p. 2131 - 2134 (2007)
The Cu(I)-catalyzed alkyne-azide [2 + 3] cycloaddition has been demonstrated to be an effective and orthogonal conjugation reaction to covalently immobilize biomolecules on magnetic nanoparticles (MNPs). The azido group on the MNP surface provides better