82373-94-2 Usage
Description
2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside, also known as THSG, is a polyphenolic compound derived from the plant Polygoni Multiflori. It is characterized by its unique structure with four hydroxyl groups and a β-D-glucoside moiety attached to the stilbene backbone. 2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside exhibits potent antioxidant and free radical scavenging properties, making it a promising candidate for various applications in different industries.
Uses
Used in Pharmaceutical Applications:
2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside is used as a therapeutic agent for its antioxidant and free radical scavenging properties. It helps protect against oxidative damage by attenuating free radicals and upregulating antioxidant and detoxifying enzymes. This makes it a potential candidate for the treatment of various diseases and conditions associated with oxidative stress.
Used in Cell Protection Applications:
In the field of cell biology, 2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside is used as a protective agent for UB/OC-2 cells against H2O2-induced autophagy and apoptosis in vitro. Its ability to safeguard cells from oxidative damage makes it a valuable tool in research and potential therapeutic applications.
Used in Antioxidant Formulations:
2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside is used as an antioxidant ingredient in various formulations, such as dietary supplements, skincare products, and nutraceuticals. Its potent antioxidant properties contribute to the overall health and well-being of individuals, as well as the preservation and stability of products.
Used in Food and Beverage Industry:
In the food and beverage industry, 2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside is used as a natural antioxidant to extend the shelf life of products and protect them from oxidative spoilage. Its ability to scavenge free radicals and prevent lipid peroxidation makes it a valuable additive for maintaining the quality and safety of food products.
Used in Cosmetics and Personal Care Industry:
2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside is used as an active ingredient in cosmetics and personal care products for its antioxidant and skin protective properties. It can be incorporated into creams, lotions, and serums to provide anti-aging benefits, protect the skin from environmental stressors, and promote overall skin health.
Biochem/physiol Actions
2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside induces the expression and enhances the activity of EPO. The compound stimulates mitochondrial biogenesis, and expression of hemoglobin in non-hematopoietic cells. 2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside has demonstrated protective effects in cardiovascular disease and ischemia models.
Physiological effects
Stilbene glycosides have the functions of brain protection, free radical scavenging, blood lipid lowering, liver protection, anti-tumor, vasodilation, and inhibition of atherosclerosis.
Check Digit Verification of cas no
The CAS Registry Mumber 82373-94-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,3,7 and 3 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 82373-94:
(7*8)+(6*2)+(5*3)+(4*7)+(3*3)+(2*9)+(1*4)=142
142 % 10 = 2
So 82373-94-2 is a valid CAS Registry Number.
InChI:InChI=1/C20H22O9/c21-9-15-16(25)17(26)18(27)20(28-15)29-19-11(7-13(23)8-14(19)24)4-1-10-2-5-12(22)6-3-10/h1-8,15-18,20-27H,9H2/b4-1+/t15-,16-,17+,18-,20+/m1/s1
82373-94-2Relevant articles and documents
Water-Assisted/Water-Accelerated Photoreaction of trans-2,3,4′,5-Tetrahydroxystilbene-2- O-β- d -glucoside from the Roots of Polygonum multiflorum
Bao, Ni-Man,Dai, Jin,Liao, Ning-Ling,Ying, Wen-Feng,Zhao, Rong-Hua
, p. 5086 - 5092 (2020/05/22)
The photoreaction of 2,3,4′,5-tetrahydroxystilbene-2-O-β-d-glucoside (TSG) has been investigated. Water-assisted/water-accelerated photodimerization of trans-TSG favored the formation of syn-head-to-tail [2 + 2] photocyclobutane under 365 nm irradiation as a result of hydrophobic association and a fluorescent solute-solute aggregate from their excited singlet states. In contrast, irradiation with 254 nm led to [2 + 2] photocycloreversion. The two cyclobutane dimers were first obtained through straightforward photoreaction and identified as multiflorumiside A and multiflorumiside C through the detailed analysis of high-resolution electrospray ionization mass spectrometry and one- and two-dimensional nuclear magnetic resonance. Therefore, trans-TSG should be protected from light and water.
Isomeric effect on H/D exchange of resveratrol studied by NMR spectroscopy
Jiang, Haipeng,Fang, Hanjun,Jiang, Ling,Zheng, Limin,Wang, Nian,Zheng, Anmin,Deng, Feng,Liu, Maili
experimental part, p. 2281 - 2286 (2011/10/12)
Resveratrol (3,5,4′-trihydroxylstilbene), a phytoalexin in response to injury or fungal attack, is found in grapes and other food products. It has been well documented that the compound has beneficial effects as hypolipidemic, anticancer, antiviral, neuro
