82378-47-0 Usage
Description
(2R)-2-(1-Methylethyl)oxirane, also known as isopropyl oxirane, is a colorless liquid with a faint, sweet odor. It is a chemical compound that is commonly used as a solvent, intermediate, and in the production of other chemicals such as pharmaceuticals, agrochemicals, and polymers.
Uses
Used in Chemical Production:
(2R)-2-(1-Methylethyl)oxirane is used as a solvent and intermediate in the production of various chemicals, including pharmaceuticals, agrochemicals, and polymers. It plays a crucial role in the synthesis of these compounds, enabling the creation of a wide range of products.
Used in Epoxy Resin Synthesis:
(2R)-2-(1-Methylethyl)oxirane is used as a key component in the synthesis of epoxy resins. These resins are essential in various industries, including coatings, adhesives, and composite materials, due to their excellent adhesion, mechanical properties, and chemical resistance.
Used in Specialty Chemical Production:
(2R)-2-(1-Methylethyl)oxirane is also used as an intermediate in the production of specialty chemicals. These chemicals are used in various applications, such as fragrances, flavors, and other industrial processes, where their unique properties are required.
Used in Food Products:
Although present in trace amounts, (2R)-2-(1-Methylethyl)oxirane can be found in some food products like baked goods, fruits, and alcoholic beverages. Its presence is generally considered safe, but it is important to handle this compound with care due to its potential harmful effects if inhaled, ingested, or causing skin and eye irritation.
Check Digit Verification of cas no
The CAS Registry Mumber 82378-47-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,3,7 and 8 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 82378-47:
(7*8)+(6*2)+(5*3)+(4*7)+(3*8)+(2*4)+(1*7)=150
150 % 10 = 0
So 82378-47-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H10O/c1-4(2)5-3-6-5/h4-5H,3H2,1-2H3/t5-/m0/s1
82378-47-0Relevant articles and documents
CRYSTALLINE FORMS OF A CD73 INHIBITOR
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, (2021/03/05)
The present invention relates to crystalline forms of 5-[5-[2-isopropylcyclopropyl] -6-methyl-pyridazin-3-yl]-1H-pyrimidine-2,4-dione, and pharmaceutical compositions comprising them, which inhibit the activity of CD73 and are useful for treating cancer.
Total Synthesis and Biological Evaluation of the Glycosylated Macrocyclic Antibiotic Mangrolide A
Hattori, Hiromu,Roesslein, Joel,Caspers, Patrick,Zerbe, Katja,Miyatake-Ondozabal, Hideki,Ritz, Daniel,Rueedi, Georg,Gademann, Karl
, p. 11020 - 11024 (2018/07/31)
The macrocyclic antibiotic mangrolide A has been described to exhibit potent activity against a number of clinically important Gram-negative pathogens. Reported is the first enantioselective total synthesis of mangrolide A and derivatives. Salient features of this synthesis include a highly convergent macrocycle preparation, stereoselective synthesis of the disaccharide moiety, and two β-selective glycosylations. The synthesis of mangrolide A and its analogues enabled the re-examination of its activity against bacterial pathogens, and only minimal activity was observed.
SMALL MOLECULE COMPOUNDS SELECTIVE AGAINST GRAM-NEGATIVE BACTERIAL INFECTIONS
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Paragraph 0321; 0324; 0325, (2016/01/30)
The described invention provides fully synthetic, biologically active mangrolide A. It describes schemes to chemically synthesize mangrolide A, intermediates and analogs of mangrolide A, and their antibacterial activity.
