82386-89-8 Usage
Description
2-Chloro-5-trifluoromethylbenzaldehyde is an organic compound characterized by the presence of a chlorine atom at the 2nd position and a trifluoromethyl group at the 5th position on a benzene ring. It is an aromatic aldehyde with a molecular formula of C8H3ClF3O and a molecular weight of approximately 200.57 g/mol. 2-Chloro-5-trifluoromethylbenzaldehyde exhibits chemical reactivity due to the presence of the aldehyde group, making it a versatile building block in organic synthesis.
Uses
Used in Pharmaceutical and Chemical Industries:
2-Chloro-5-trifluoromethylbenzaldehyde is used as a reactant in the three-component reaction involving 2-halogenated aromatic aldehydes, 1H-benzo[d]imidazol-5-amine, and cyclohexane-1,3-diones. This reaction leads to the formation of imidazoquinolinoacridinone derivatives, which are valuable compounds with potential applications in pharmaceutical and chemical research.
Used in Material Science:
In the field of material science, 2-Chloro-5-trifluoromethylbenzaldehyde is utilized in the gas-phase chemical derivatization of poly(tetrafluoroethylene) (PTFE) and poly(ethylene terephthalate) (PET) using gas plasma. This process allows for the modification of the surface properties of these polymers, enhancing their compatibility with other materials and improving their overall performance in various applications, such as coatings, films, and adhesives.
Check Digit Verification of cas no
The CAS Registry Mumber 82386-89-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,3,8 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 82386-89:
(7*8)+(6*2)+(5*3)+(4*8)+(3*6)+(2*8)+(1*9)=158
158 % 10 = 8
So 82386-89-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H4ClF3O/c9-7-2-1-6(8(10,11)12)3-5(7)4-13/h1-4H
82386-89-8Relevant articles and documents
Practical Cu(OAc)2/TEMPO-catalyzed selective aerobic alcohol oxidation under ambient conditions in aqueous acetonitrile
Jiang, Jian-An,Du, Jia-Lei,Wang, Zhan-Guo,Zhang, Zhong-Nan,Xu, Xi,Zheng, Gan-Lin,Ji, Ya-Fei
supporting information, p. 1677 - 1681 (2014/03/21)
We reported a ligand-and additive-free Cu(OAc)2/TEMPO catalyst system that enables efficient and selective aerobic oxidation of a broad range of primary and secondary benzylic alcohols, primary and secondary 1-heteroaryl alcohols, cinnamyl alcohols, and aliphatic alcohols to the corresponding aldehydes and ketones. This ambient temperature oxidation protocol is of practical features like aqueous acetonitrile as solvent, ambient air as the terminal oxidant, and low catalyst loading, presenting a potential value in terms of both economical and environmental considerations. Based on the experimental observations, a plausible reaction mechanism was proposed.
Tricyclic psychotropic agents containing two chalcogen atoms in the central ring: Derivatives of 11H-dibenz[b,f]-1,4-oxathiepin
Sindelar,Holubek,Ryska,et al.
, p. 967 - 983 (2007/10/02)
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