82413-55-6

Basic information

• Product Name: 25,26-didehydroponasterone A
• CAS NO: 82413-55-6
• Molecular Weight: 462.627
• Mol File: 82413-55-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 25,26-didehydroponasterone A(CAS DataBase Reference)
• NIST Chemistry Reference: 25,26-didehydroponasterone A(82413-55-6)
• EPA Substance Registry System: 25,26-didehydroponasterone A(82413-55-6)

Safety Data

• Hazardous Substances Data: 82413-55-6(Hazardous Substances Data)

Upstream product

• 84507-66-4 20-hydroxyecdysone 2,3:20,22-diacetonide 
• 19404-87-6 20-hydroxyecdysone-2,3,22-triacetate 

Downstream Products

• 13408-48-5 ponasterone A 

Relevant articles and documents

Naturally occurring 20, 26-dihydroxyecdysone exists as two C-25 epimers which exhibit different degrees of moulting hormone activity

20,26-Dihydroxyecdysone (20,26-ECD) isolated from Vitex canescens, V. glabrata and V. pinnata has been shown to exist as two C-25 epimers. Synthesis and separation of the two epimers were accomplished and they exhibited different degree of moulting hormone activity in the Musca assay.

Asymmetric dihydroxylation of stachysterone C: Stereoselective synthesis of 24-epi-abuasterone

Stachysterone C was synthesized from 20-hydroxyecdysone (20-ECD). Sharpless asymmetric dihydroxylation of this rare ecdysteroid using osmium tetroxide and a chiral ligand afforded 24-epi-abutasterone, another rare ecdysteroid, and its C-24 epimer, abutasterone. High diastereomeric excess of the former ecdysteroid was obtained when the chiral ligands dihydroquinidine 1,4-phthalazinediyl diether and dihydroquinidine 2,5-diphenyl-4,6-pyrimidinediyl diether were employed. The two C-24 epimeric ecdysteroids exhibited similar moulting hormone activity in the Musca bioassay. However, they were significantly less active than 20-ECD.