82577-50-2Relevant articles and documents
Regiospecific synthesis of polysubstituted furans with mono- to tricarboxylates from various sulfonium acylmethylides and acetylenic esters
Dong, Jun,Du, Hongguang,Xu, Jiaxi
, p. 25034 - 25038 (2019/08/22)
Polysubstituted furans were prepared in moderate to good yields from various sulfur ylides and alkyl acetylenic carboxylates. The direct reactions of dimethylsulfonium acylmethylides with dialkyl acetylenedicarboxylates afforded dialkyl furan-3,4-dicarboxylates through a tandem sequence of Michael addition, intramolecular nucleophilic addition, 4π ring opening, intramolecular Michael addition, and elimination. The method was extended to synthesize furan-3-carboxylate, -2,4-dicarboxylates, and -2,3,4-tricarboxylates as well. The current method provides a direct and simple strategy in the synthesis of structurally diverse polysubstituted furans with mono to tricarboxylate groups from safe and readily available dimethylsulfonium acylmethylides and different alkyl acetylenic carboxylates.
A mild, convenient and efficient single-step method for the synthesis of polysubstituted furans via ammonium ylide routes
Fan, Mingjin,Guo, Lina,Liu, Xueyuan,Liu, Weimin,Liang, Yongmin
, p. 391 - 396 (2007/10/03)
A new and convenient cyclization method for the synthesis of polysubstituted furans in a single-step via ammonium ylide routes was reported. In this process, dimethyl acetylenedicarboxylate reacted with ammonium ylide to produce polysubstituted furan in the presence of anhydrous K2CO 3 at room temperature. It is very economical, environmentally friendly and very easy to carry out. Georg Thieme Verlag Stuttgart.
SYNTHESIS AND ELECTROPHILIC SUBSTITUTION REACTIONS OF 2-ARYL-3,4-BIS(CARBOMETHOXY)FURANS
Oleinik, A. F.,Adamskaya, E. V.,Novitskii, K. Yu.
, p. 337 - 340 (2007/10/02)
The thermal decomposition of the products of hydrogenation of the adducts obtained from arylfurans and dimethyl acetylenedicarboxylate leads to the formation of 2-aryl-3,4-bis(carbomethoxy)furans.The bromination of these compounds takes place in the 5 pos