82791-70-6

Basic information

• Product Name: Propanamide, N-[4-(hydroxyphenylmethyl)-3-pyridinyl]-2,2-dimethyl-
• CAS NO: 82791-70-6
• Molecular Formula: C17H20N2O2
• Molecular Weight: 284.358
• Mol File: 82791-70-6.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Propanamide, N-[4-(hydroxyphenylmethyl)-3-pyridinyl]-2,2-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanamide, N-[4-(hydroxyphenylmethyl)-3-pyridinyl]-2,2-dimethyl-(82791-70-6)
• EPA Substance Registry System: Propanamide, N-[4-(hydroxyphenylmethyl)-3-pyridinyl]-2,2-dimethyl-(82791-70-6)

Safety Data

• Hazardous Substances Data: 82791-70-6(Hazardous Substances Data)

Upstream product

• 3282-30-2 pivaloyl chloride 
• 462-08-8 pyridin-3-ylamine 
• 70298-88-3 N-(pyridin-3-yl)pivalamide 
• 100-52-7 benzaldehyde 

Downstream Products

• 125867-45-0 10-phenyl-6,7,8,9-terahydrobenzo<1,7>naphtyridine 
• 125867-42-7 4-phenyl-1,2-dihydropyrido<3,4-d>-2-pyrimidinone 
• 3810-18-2 1,3-dihydro-5-phenyl-2H-pyrido<3,4-e>-1,4-diazepin-2-one 
• 15505-59-6 3-benzyloxycarbonylaminomethylcarbonylamino-4-benzoylpyridine 
• 112175-42-5 3-tert-butoxycarbonylaminomethylcarbonylamino-4-benzoylpyridine 
• 112175-39-0 1,3-dihydro-1-methyl-5-phenyl-2H-pyrido<3,4-e>-1,4-diazepin-2-one 
• 3810-11-5 (3-aminopyridin-4-yl)(phenyl)methanone 
• 112175-38-9 N-(4-benzoylpyridin-3-yl)-2,2-dimethylpropionamide 

Relevant articles and documents

Quinolinones as Inhibitors of Translation Initiation Complex

Provided herein are compounds and pharmaceutical compositions comprising quinolinones. The quinolinones and compositions thereof are useful as eukaryotic translation initiation factor 4F (eIF4F) complex modulators.

COMPOUNDS

The present invention provides a compound incorporating a group of formula (I) wherein: 1 of X, Y and Z is nitrogen and the other 2 are carbon; R" is hydrogen, methyl, ethyl or propyl; and W represents hydrogen, carbon, nitrogen, oxygen or sulphur; or incorporating a salt, hydrate or solvate of a group of formula (I); as well as therapeutic uses of these compounds, in particular as inhibitors of protein kinase activity and in the treatment of inflammation, inflammatory conditions and cancer.

NEW PYRIDIN-3-AMINE DERIVATIVES

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