82807-53-2

Basic information

• Product Name: Phenol, 4-methyl-2-(4-morpholinylmethyl)-
• CAS NO: 82807-53-2
• Molecular Formula: C12H17NO2
• Molecular Weight: 207.272
• Mol File: 82807-53-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Phenol, 4-methyl-2-(4-morpholinylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-methyl-2-(4-morpholinylmethyl)-(82807-53-2)
• EPA Substance Registry System: Phenol, 4-methyl-2-(4-morpholinylmethyl)-(82807-53-2)

Safety Data

• Hazardous Substances Data: 82807-53-2(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 5720-05-8 4-methylphenylboronic acid 
• 106-44-5 p-cresol 
• 50-00-0 formaldehyd 
• 75-09-2 dichloromethane 
• 569646-48-6 [2-(tert-butyl-diphenyl-silanyloxy)-5-methyl-benzyl]-dimethyl-amine 
• 569646-46-4 4-Methyl-2-{[morpholin-4-ylmethyl-((R)-1-phenyl-ethyl)-amino]-methyl}-phenol 
• 237431-64-0 6-methyl-3-[(1R)-1-phenylethyl]3,4-dihydro-2H-1,3-benz[e]oxazine 
• 7204-35-5 2-(dimethylamino-methyl)-4-methyl-phenol 
• 569646-47-5 4-Methyl-2-[((R)-1-phenyl-ethylamino)-methyl]-phenol 
• 67853-12-7 (2-hydroxy-5-methyl-benzyl)-trimethyl-ammonium; iodide 

Relevant articles and documents

Cu(II)-Catalyzed ortho-Selective Aminomethylation of Phenols

A Cu(II)-catalyzed ortho-selective functionalization of free phenols with trifluoroborates to afford Csp2-Csp3 coupling products under mild conditions has been developed. A variety of functional groups on the phenol and the potassium aminomethyltrifluoroborate substrates were found compatible, furnishing the corresponding products in moderate to excellent yields. A single-electron transfer radical coupling mechanism involving a six-membered transition state is proposed to rationalize the high levels of ortho-selectivity in the reaction. This protocol provides straightforward access to ortho-aminomethyl-substituted phenols, unnatural amino acids and other bioactive small molecules.

Synthesis of N-[2-hydroxy-4(5)-methyl- and -5-(methylcyclohexyl)benzyl] morpholines as antioxidants for transformer oils

Aminomethylation of m- and p-cresols and of p-(1-methylcyclohexyl)phenol with formaldehyde and morpholine was studied. The products obtained were tested as antioxidant additives to T-1500 transformer oil.