82864-02-6

Basic information

• Product Name: R(-)-DOI HYDROCHLORIDE POTENT AND SELECT IVE
• Synonyms: R(-)-DOI HYDROCHLORIDE POTENT AND SELECT IVE;(R)-(-)-2,5-dimethoxy-4-iodoamphetamine hydrochloride;(-)-2,5-Dimethoxy-4-iodoamphetamine hydrochloride, (-)-1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride;(-)-2,5-Dimethoxy-4-iodoamphetamine hydrochloride (R)(-)-DOI hydrochloride
• CAS NO: 82864-02-6
• Molecular Formula: C11H16INO2HCl
• Molecular Weight: 357.62
• Mol File: 82864-02-6.mol
• Article Data: 0

Chemical Properties

• Melting Point: 232 °C(Solv: isopropanol (67-63-0))
• Boiling Point: 361.5 °C at 760 mmHg
• Flash Point: 172.5 °C
• Appearance: white/
• Solubility: H2O: ≥20mg/mL
• CAS DataBase Reference: R(-)-DOI HYDROCHLORIDE POTENT AND SELECT IVE(CAS DataBase Reference)
• NIST Chemistry Reference: R(-)-DOI HYDROCHLORIDE POTENT AND SELECT IVE(82864-02-6)
• EPA Substance Registry System: R(-)-DOI HYDROCHLORIDE POTENT AND SELECT IVE(82864-02-6)

Safety Data

• RIDADR: 2811
• WGK Germany: 3
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 82864-02-6(Hazardous Substances Data)

Usage

Description

R(-)-DOI HYDROCHLORIDE POTENT AND SELECTIVE is a chiral compound that belongs to the family of psychoactive drugs known as tryptamines. It is a potent and selective agonist of the 5-HT2A serotonin receptor, which plays a significant role in various physiological and psychological processes. The R(-) enantiomer is known for its high potency and selectivity, making it a valuable compound for research and potential therapeutic applications.
Used in Pharmaceutical Industry:
R(-)-DOI HYDROCHLORIDE POTENT AND SELECTIVE is used as a research chemical for the development of new drugs targeting the 5-HT2A receptor. Its high potency and selectivity make it an ideal candidate for studying the receptor's role in various disorders and for developing more effective treatments.
Used in Neuroscientific Research:
In the field of neuroscientific research, R(-)-DOI HYDROCHLORIDE POTENT AND SELECTIVE is used as a research tool to investigate the function and mechanisms of the 5-HT2A receptor. This helps researchers to better understand the receptor's role in cognitive processes, mood regulation, and other neurological functions.
Used in Stereospecific Synthesis:
R(-)-DOI HYDROCHLORIDE POTENT AND SELECTIVE is used as a useful reagent in the stereospecific synthesis of amphetamines via multi-step reactions involving corresponding aryl propanol. This application is particularly relevant in the development of new psychoactive substances and the study of their effects on the central nervous system.

Biochem/physiol Actions

Potent and selective 5-HT2 serotonin receptor agonist that crosses the blood-brain barrier; more potent enantiomer of ±-DOI hydrochloride.