83-94-3 Usage
Description
Tabernanthine is an alkaloid found in Tabernanthe iboga BailI. and Stem madenia donnell-smithii R. E. Woodson. It forms colorless needles or orthorhombic plates from ethanol and is best purified by sublimation. The alkaloid has specific optical rotation and ultraviolet spectrum characteristics. Its hydrochloride salt forms colorless crystals from boiling water and has unique properties such as being soluble in chloroform, containing one methoxyl group, and being unsaturated.
Uses
Used in Pharmaceutical Industry:
Tabernanthine is used as a hypotensive agent for its ability to reduce blood pressure when injected intravenously into dogs. It is effective in decreasing reflex hypertension induced by carotid occlusion and lowering both the rate and amplitude of respiration.
Used in Cardiovascular Applications:
In cardiovascular research, tabernanthine is used to study its effects on hypertension produced by the injection of adrenaline, as it has been found to increase the hypertension induced by this hormone.
Used in Respiratory Applications:
Tabernanthine is utilized in respiratory studies to understand its impact on the rate and amplitude of respiration, as it has been observed to decrease these parameters in dogs.
Used in Neurotransmission Research:
Tabernanthine is used in research to study its effects on neurotransmission, particularly its ability to prolong the hypotension resulting from the injection of acetylcholine, which plays a crucial role in various physiological processes.
References
Delourme-Houde., An .. Pharm. Fr., 4, 30 (1946)
Bartlett, Dickel, Taylor.,J. Amer. Chem. Soc., 80, 126 (1958)
Walls, Collera, Sandoval., Tetrahedron, 2, 173 (1958)
Pharmacology:
Delourme-Houde., Ann. Pharm. Fr., 4, 30 (1946)
Check Digit Verification of cas no
The CAS Registry Mumber 83-94-3 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 8 and 3 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 83-94:
(4*8)+(3*3)+(2*9)+(1*4)=63
63 % 10 = 3
So 83-94-3 is a valid CAS Registry Number.
InChI:InChI=1/C20H26N2O/c1-3-13-8-12-9-17-19-16(6-7-22(11-12)20(13)17)15-5-4-14(23-2)10-18(15)21-19/h4-5,10,12-13,17,20-21H,3,6-9,11H2,1-2H3/t12-,13+,17+,20+/m1/s1