83014-44-2

Basic information

• Product Name: QUIN 2
• Synonyms: 2-[(2-BIS-[CARBOXYMETHYL]AMINO-5-METHYLPHENOXY)METHYL]-6-METHOXY-8-BIS[CARBOXYMETHYL]AMINOQUINOLINE;QUIN 2;Quin-2, free acid;2-[(2-Amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-N,N,N',N'-tetraaceticacid;QUETIAPINEFUMARATE;Glycine, N-(2-((8-(bis(carboxymethyl)amino)-6-methoxy-2-quinolinyl)methoxy)-4-methylphenyl)-N-(carboxymethyl)-;N-(2-((8-(Bis(carboxymethyl)amino)-6-methoxy-2-quinolinyl)methoxy)-4-methylphenyl)-N-(carboxymethyl)glycine;Quin II
• CAS NO: 83014-44-2
• Molecular Formula: C26H27N3O10
• Molecular Weight: 541.51
• Mol File: 83014-44-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 164-166℃
• Boiling Point: 831.6°C at 760 mmHg
• Flash Point: 456.7°C
• Appearance: /
• Density: 1.494g/cm³
• Vapor Pressure: 2.58E-29mmHg at 25°C
• Refractive Index: 1.688
• CAS DataBase Reference: QUIN 2(CAS DataBase Reference)
• NIST Chemistry Reference: QUIN 2(83014-44-2)
• EPA Substance Registry System: QUIN 2(83014-44-2)

Safety Data

• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36:Wear suitable prot
• Hazardous Substances Data: 83014-44-2(Hazardous Substances Data)

Usage

Description

QUIN 2 is a quinoline-based fluorescent Ca2+ indicator compound that functions as an intracellular Ca2+ concentration indicator and also serves as a buffer for intracellular Ca2+ levels.

Uses

Used in Biomedical Research:
QUIN 2 is used as a fluorescent Ca2+ indicator for monitoring intracellular Ca2+ concentration changes in various cell types. This allows researchers to study the role of Ca2+ ions in cellular processes and signaling pathways.
Used in Neurobiology:
In neurobiology, QUIN 2 is used as a tool to investigate the role of Ca2+ ions in neuronal function and neurotransmission. It helps researchers understand the mechanisms of synaptic plasticity, neuronal excitability, and the impact of Ca2+ on neuronal health and disease.
Used in Pharmacological Studies:
QUIN 2 is used as a Ca2+ buffer in pharmacological studies to control intracellular Ca2+ levels and study the effects of drugs on Ca2+ homeostasis. This helps in evaluating the efficacy and safety of potential therapeutic agents that target Ca2+ signaling pathways.
Used in Environmental and Toxicological Research:
In environmental and toxicological research, QUIN 2 is used as a tool to assess the impact of environmental toxins and pollutants on intracellular Ca2+ levels. This aids in understanding the mechanisms of toxicity and developing strategies for mitigating the harmful effects of these substances on living organisms.

InChI:InChI=1/C26H27N3O10/c1-15-3-6-19(28(10-22(30)31)11-23(32)33)21(7-15)39-14-17-5-4-16-8-18(38-2)9-20(26(16)27-17)29(12-24(34)35)13-25(36)37/h3-9H,10-14H2,1-2H3,(H,30,31)(H,32,33)(H,34,35)(H,36,37)