83314-83-4Relevant articles and documents
Methotrexate Analogues. 16. Importance of the Side-Chain Amide Carbonyl Group as a Structural Determinant of Biological Activity
Rosowsky, A.,Forsch, R.
, p. 1454 - 1459 (2007/10/02)
N-amino>benzyl>-L-glutamic acid ("deoxyaminopterin", 1), a new aminopterin analogue containing a CH2 group in the side chain in place of the amide C=O, was synthesized by condensation of 2,4-diamino-6-(bromomethyl)pterid