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83343-42-4

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83343-42-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 83343-42-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,3,4 and 3 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 83343-42:
(7*8)+(6*3)+(5*3)+(4*4)+(3*3)+(2*4)+(1*2)=124
124 % 10 = 4
So 83343-42-4 is a valid CAS Registry Number.

83343-42-4Downstream Products

83343-42-4Relevant articles and documents

(S)- and (R)-8-(di-n-propylamino)-6,7,8,9-tetrahydro-3H-benz[e]indole-1- carbaldehyde: A new class of orally active 5-HT(1A)-receptor agonists

Stjernlof,Gullme,Elebring,Andersson,Wikstrom,Lagerquist,Svensson,Ekman,Carlsson,Sundell

, p. 2059 - 2065 (2007/10/02)

The enantiomers of 6,7,8,9-tetrahydro-N,N-di-n-propyl-3H-benz[e]indol-8- amine (S-(-)-2b and R-(+)-2b) and their corresponding 1-formyl analogs (S-(- )-6 and R-(+)-6 were prepared and evaluated pharmacologically for serotonergic and dopaminergic activity. The introduction of a formyl group in the 1-position shifted the pharmacological profile of 2b from a mixed D2/5- HT(1A) agonists to a selective 5-HT(1A) agonist (6). The enantiomers of 6 were agonists with full intrinsic activity and had an affinity comparable to that of 8-hydroxy-2-(di-n-propylamino)tetrahydronaphthalene (8-OH-DPAT). In contrast to 8-OH-DPAT, the enantiomers of compound 6 were found to have good oral availability.

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