83512-85-0 Usage
Description
Carboxymethyl chitosan is a biocompatible and biodegradable polymeric modifier derived from chitosan, a natural polysaccharide found in the shells of crustaceans. It possesses unique chemical properties, such as the ability to form a gel with water and a lower degree of substitution than 5-00936. These properties make it a versatile material for various applications in different industries.
Uses
Used in Environmental Applications:
Carboxymethyl chitosan is used as an absorbent for the removal of mercury ions from contaminated water sources. Its high affinity for heavy metal ions allows for efficient and eco-friendly remediation of polluted environments.
Used in Textile Industry:
Carboxymethyl chitosan is used as a binding agent for silver nanoparticle-coated cotton fabric. This application enhances the antimicrobial properties of the fabric, making it suitable for use in medical and hygiene products.
Used in Pharmaceutical Industry:
Carboxymethyl chitosan is used as a sustained or controlled release drug delivery system. Its biocompatibility and biodegradability make it an ideal candidate for delivering therapeutic agents in a controlled manner, improving patient compliance and treatment outcomes.
Used in Drug Delivery Systems:
Carboxymethyl chitosan is used as a pH-responsive drug delivery system. Its ability to respond to changes in pH levels allows for targeted drug release in specific environments, such as the acidic conditions of the stomach or the neutral pH of the intestines.
Used in Gene Delivery:
Carboxymethyl chitosan is used as a permeation enhancer in gene delivery systems. Its ability to facilitate the transport of genetic material across biological barriers makes it a promising tool for gene therapy applications.
Used in Nanocarriers:
Carboxymethyl chitosan is used as a coating material on nanocarriers for drug delivery. Its biocompatibility and ability to form gels with water make it an ideal candidate for encapsulating and protecting therapeutic agents during delivery, improving their stability and bioavailability.
Chitosan VS Carboxymethyl Chitosan
Compared to chitosan, Carboxymethyl chitosan not only can be applied in wider pH ranges of water since its higher stability, but also has a higher hydrophilicity . The larger specific surface area, a multitude of functional groups and higher hydrophilicity of Carboxymethyl chitosan are expected to play an essential role in more efficiently coordinating with mental oxide and flocculate solrelieving tickle. Carboxymethyl chitosan is an amphoteric poly-saccharide that possesses pH-sensitive property, since it bears both acidic (-COOH) and basic groups (-NH2).
Preparation
Carboxymethyl chitosan can be obtained by direct alkylation of chitosan. The Carboxymethyl chitosan achieved can be in many types: N-carboxymethyl chitosan (N-CMCS), O-carboxymethyl chitosan (O-CMCS), N,O-carboxymethyl chitosan (N,O-CMCS) and N,N-carboxymethyl chitosan (N,N-CMCS). Different reaction conditions will result in the N vs. O selectivity and different degree of substitution (DS). Carboxymethyl chitosan possesses high viscosity, large hydrodynamic volume, film- and gel-forming capabilities together with the other useful properties, such as biocompatibility, biodegradation, biological activity and low toxicity, all of which make it an attractive option in connection with its use in foods and cosmetics.
Check Digit Verification of cas no
The CAS Registry Mumber 83512-85-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,5,1 and 2 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 83512-85:
(7*8)+(6*3)+(5*5)+(4*1)+(3*2)+(2*8)+(1*5)=130
130 % 10 = 0
So 83512-85-0 is a valid CAS Registry Number.
