835882-35-4 Usage
Description
Cyclohepten-1-ylboronic acid is an organic compound that serves as a versatile reagent in chemical synthesis, particularly in the preparation of substituted quinoline derivatives. It is characterized by its cycloheptene ring and boronic acid functional group, which contribute to its unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
Cyclohepten-1-ylboronic acid is used as a synthetic intermediate for the preparation of various pharmaceutical compounds, specifically substituted quinoline derivatives. These derivatives are known for their diverse range of biological activities, including antimalarial, anticancer, and antiviral properties.
Used in Organic Synthesis:
In the field of organic synthesis, cyclohepten-1-ylboronic acid is utilized as a reagent in the cyclocondensation of acylaryl amines with heteroarylacetic acids. This key step allows for the efficient synthesis of complex organic molecules with potential applications in various industries, such as pharmaceuticals, agrochemicals, and materials science.
Used in Material Science:
Cyclohepten-1-ylboronic acid may also find applications in material science, where its unique structure and reactivity can be exploited to develop new materials with specific properties. These materials could be used in various applications, such as sensors, catalysts, or advanced materials for electronics and energy storage.
Check Digit Verification of cas no
The CAS Registry Mumber 835882-35-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,3,5,8,8 and 2 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 835882-35:
(8*8)+(7*3)+(6*5)+(5*8)+(4*8)+(3*2)+(2*3)+(1*5)=204
204 % 10 = 4
So 835882-35-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H13BO2/c9-8(10)7-5-3-1-2-4-6-7/h5,9-10H,1-4,6H2
835882-35-4Relevant articles and documents
Copper-catalyzed tri- or tetrafunctionalization of alkenylboronic acids to prepare tetrahydrocarbazol-1-ones and indolo[2,3-a]carbazoles
Bi, Hong-Yan,Li, Cheng-Jing,Liang, Cui,Mo, Dong-Liang,Wei, Cui
, p. 5815 - 5821 (2020/09/21)
We describe a cascade strategy for tri- or tetrafunctionalization of alkenylboronic acids to prepare diverse tetrahydrocarbazol-1-ones and indolo[2,3-a]carbazoles in good yields withN-hydroxybenzotriazin-4-one (HOOBT) and arylhydrazines as oxygen and nitrogen sources, respectively. Mechanistic studies reveal that the domino reaction undergoes the copper-catalyzed Chan-Lam reaction, [2,3]-rearrangement, nucleophilic substitution, oxidation and sequential [3,3]-rearrangement over five steps in a one-pot reaction. The reaction shows a broad substrate scope and tolerates a wide range of functional groups. More importantly, the reaction is easily performed at gram scales and the product is purified by simple extraction, washing, and recrystallization without flash column chromatography. The present protocol features easily available starting materials, high site-marked functionalization, five-step cascade in one pot, multiple C-C/C-O/C-N bond formation, and diversity of indole motifs.
