83655-43-0Relevant articles and documents
Studies on Simplified Ergoline Derivatives. A General Six-Step Synthesis of Phenyl-Substituted 4-Methyl-3,4,4a,5,6,10b-hexahydrobenzoquinolin-1-(2H)-one Analogs (1)
Salley, John J.,Glennon, Richard A.
, p. 545 - 550 (2007/10/02)
This communication outlines the development of a novel, general synthetic route to substituted α-tetralones 5, their subsequent conversion to the α,β-unsaturated ketones 11, and an improved, one-step transformation of 11 to the tricyclic title compounds 1.Thus, substituted derivatives of 1 can be prepared in six steps from simple benzaldehydes, or, in three steps from more readily available α-tetralones.
