83727-08-6

Basic information

• Product Name: 5-[2-(2-Benzoyl-5-methylsulfanyl-pyrrol-1-yl)-ethyl]-2,2-dimethyl-[1,3]dioxane-4,6-dione
• Synonyms: 5-[2-(2-Benzoyl-5-methylsulfanyl-pyrrol-1-yl)-ethyl]-2,2-dimethyl-[1,3]dioxane-4,6-dione
• CAS NO: 83727-08-6
• Molecular Weight: 387.456
• Mol File: 83727-08-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-[2-(2-Benzoyl-5-methylsulfanyl-pyrrol-1-yl)-ethyl]-2,2-dimethyl-[1,3]dioxane-4,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[2-(2-Benzoyl-5-methylsulfanyl-pyrrol-1-yl)-ethyl]-2,2-dimethyl-[1,3]dioxane-4,6-dione(83727-08-6)
• EPA Substance Registry System: 5-[2-(2-Benzoyl-5-methylsulfanyl-pyrrol-1-yl)-ethyl]-2,2-dimethyl-[1,3]dioxane-4,6-dione(83727-08-6)

Safety Data

• Hazardous Substances Data: 83727-08-6(Hazardous Substances Data)

Upstream product

• 611-74-5 N,N-dimethylbenzamide 
• 53391-61-0 2-methylthiopyrrole 
• 5617-70-9 cycl-isopropylidene cyclopropane-1,1-dicarboxylate 
• 80965-00-0 2-(methylthio)-5-benzoylpyrrole 

Downstream Products

• 80965-05-5 2-[2-(2-Benzoyl-5-methanesulfonyl-pyrrol-1-yl)-ethyl]-malonic acid dimethyl ester 
• 80965-08-8 dimethyl 5-benzoyl-1,2-dihydro-3H-pyrrolo<1,2-a>pyrrole-1,1-dicarboxylate 
• 80965-09-9 5-benzoyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid methyl ester 
• 74103-06-3 Ketorolac 
• 225502-94-3 8,8-dimethyl-3-methylsulfanyl-11-phenyl-4,5-dihydro-11H-7,9,10-trioxa-3a-aza-benzo[a]cyclopenta[e]cycloocten-6-one 
• 80965-04-4 [1-[2-(4,6-dioxo-2,2-dimethyl-1,3-dioxan-5-yl)ethyl]-2-(methanesulfonyl)-5-(benzoyl)]-pyrrole 

Relevant articles and documents

An anomalous preparing of a tetrahydro-2H-oxocine fused pyrrole derivative and its acid-catalyzed rearrangement

Condensation of 5-methylthio-2-benzoylpyrrole (1) with spiro[2.5]-5,7- dioxa-6,6-dimethyloctane-4,8-dione (3) using excess mount of Nail in DMF gave an anomalous tetrahydro-2H-oxocine fused pyrrole (10), which then undergoes an acid-catalyzed rearrangement in refluxing toluene/methanol (10:1, v/v) to afford the unexpected anti-aromatic compounds (15 and 16).