837412-26-7

Basic information

• Product Name: 3-Pyridinecarboxylic acid, 6-[(2-carboxyphenyl)amino]-5-cyano-2-methyl-, 3-ethyl ester
• CAS NO: 837412-26-7
• Molecular Formula: C17H15N3O4
• Molecular Weight: 325.324
• Mol File: 837412-26-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarboxylic acid, 6-[(2-carboxyphenyl)amino]-5-cyano-2-methyl-, 3-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxylic acid, 6-[(2-carboxyphenyl)amino]-5-cyano-2-methyl-, 3-ethyl ester(837412-26-7)
• EPA Substance Registry System: 3-Pyridinecarboxylic acid, 6-[(2-carboxyphenyl)amino]-5-cyano-2-methyl-, 3-ethyl ester(837412-26-7)

Safety Data

• Hazardous Substances Data: 837412-26-7(Hazardous Substances Data)

Upstream product

• 64119-42-2 ethyl 6-chloro-5-cyano-2-methylnicotinate 
• 118-92-3 anthranilic acid 

Relevant articles and documents

Synthesis of derivatives of 8-cyano-6-ethoxycarbonyl-3-hydroxy-5- methylimidazo[1,2-a]pyridine and 9-alkoxycarbonyl- (or 9-carboxy)-3- ethoxycarbonyl-2-methyl-10H-benzo[b]-1,8-naphthyridine-5-one from the reaction of 2-chloro-5-ethoxycarbonyl-6-methylnicotinonitrile with amino acids

2-Substituted 8-cyano-6-ethoxycarbonyl-3-hydroxy-5-methylimidazo[1,2-a] pyridine was formed from the interaction of 2-chloro-5-ethoxycarbonyl-6- methylnicotinonitrile with α-amino acids in DMF. The same nitrile on boiling with anthranilic acid or its esters in butanol gave, respectively, 2-(2-carboxyanilino)- or 2-(2-alkoxycarbonylanilino)-5-ethoxycarbonyl-6- methylnicotinonitriles which cyclized on heating in PPA to give 9-alkoxycarbonyl(or 9-carboxy)-3-ethoxycarbonyl-2-methyl-10H-benzo[b]-1,8- naphthyridin-5-ones.