83816-95-9

Basic information

• Product Name: (S)-2-{(S)-4-Carboxy-4-[(S)-4-carboxy-4-(4-methylamino-benzoylamino)-butyrylamino]-butyrylamino}-pentanedioic acid
• Synonyms: (S)-2-{(S)-4-Carboxy-4-[(S)-4-carboxy-4-(4-methylamino-benzoylamino)-butyrylamino]-butyrylamino}-pentanedioic acid
• CAS NO: 83816-95-9
• Molecular Weight: 538.511
• Mol File: 83816-95-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-{(S)-4-Carboxy-4-[(S)-4-carboxy-4-(4-methylamino-benzoylamino)-butyrylamino]-butyrylamino}-pentanedioic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-{(S)-4-Carboxy-4-[(S)-4-carboxy-4-(4-methylamino-benzoylamino)-butyrylamino]-butyrylamino}-pentanedioic acid(83816-95-9)
• EPA Substance Registry System: (S)-2-{(S)-4-Carboxy-4-[(S)-4-carboxy-4-(4-methylamino-benzoylamino)-butyrylamino]-butyrylamino}-pentanedioic acid(83816-95-9)

Safety Data

• Hazardous Substances Data: 83816-95-9(Hazardous Substances Data)

Upstream product

• 79974-14-4 N-<4-<<(benzyloxy)carbonyl>methylamino>benzoyl>-L-glutamic acid α-benzyl ester 
• 83816-91-5 (S)-2-((S)-4-Benzyloxycarbonyl-4-{(S)-4-benzyloxycarbonyl-4-[4-(benzyloxycarbonyl-methyl-amino)-benzoylamino]-butyrylamino}-butyrylamino)-pentanedioic acid dibenzyl ester 

Downstream Products

• 41600-14-0 N-methylamino>benzoyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-γ-glutamic acid 

Relevant articles and documents

A Synthetic Approach to Poly(γ-glutamyl) Conjugates of Methotrexate

Methotrexate poly(γ-L-glutamate)s bearing two and three glutamate units above that present in methotrexate have been synthesized by extension of a previously described route used to synthesize the lower conjugate bearing one added glutamate unit.Key steps