83948-53-2 Usage
Description
tert-Butyl 3-bromopropylcarbamate is a chemical compound that serves as an intermediate in the synthesis of various organic compounds. It is characterized by its ability to act as an alkylating reagent, which allows it to be used in the production of a range of pharmaceuticals and polymers.
Uses
Used in Pharmaceutical Synthesis:
tert-Butyl 3-bromopropylcarbamate is used as an alkylating reagent for the synthesis of Benzydamine analogs, which are activators for soluble guanylate cyclase. This application is significant in the development of drugs targeting specific biological pathways.
Used in Cancer Research:
In the field of cancer research, tert-Butyl 3-bromopropylcarbamate is utilized for the synthesis of N-substituted chromenotriazolopyrimidine, a human murine double minute 2 (MDM2) inhibitor. MDM2 inhibitors have the potential to play a crucial role in cancer treatment by targeting proteins that regulate the cell cycle and apoptosis.
Used in Organic Chemistry:
tert-Butyl 3-bromopropylcarbamate is also used for the synthesis of protected amines from piperidine derivatives, which are essential building blocks for the creation of sulfonamide series. Sulfonamides are a class of antibiotics that have been widely used in the treatment of bacterial infections.
Used in Polymer Science:
Furthermore, tert-Butyl 3-bromopropylcarbamate can be employed for the post-polymerization quaternization of polymers. This process allows the synthesis of functional cationic polymers, which have applications in various fields, including the development of antimicrobial agents to combat resistant bacterial strains.
Check Digit Verification of cas no
The CAS Registry Mumber 83948-53-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,9,4 and 8 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 83948-53:
(7*8)+(6*3)+(5*9)+(4*4)+(3*8)+(2*5)+(1*3)=172
172 % 10 = 2
So 83948-53-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H16BrNO2/c1-8(2,3)12-7(11)10-6-4-5-9/h4-6H2,1-3H3,(H,10,11)
83948-53-2Relevant articles and documents
PHTHALOCYANINE DYE COMPOUNDS, CONJUGATES AND METHODS OF USE THEREOF
-
Paragraph 000174-000175, (2021/10/15)
Disclosed herein are phthalocyanine dyes, and conjugates thereof, useful as fluorescent reporters for bioassays, for optical imaging and as therapeutic conjugates as the photosensitizing agents in light-based therapies including photoimmuno therapy (PIT). Certain phthalocyanine dyes disclosed herein are water soluble, and possess photophysical and photochemical profiles useful for use in imaging or therapy.
Graphene Oxide Cellular Delivery of Hydrophilic Small Molecules
-
Paragraph 0069; 0071, (2017/04/04)
Unmodified graphene oxide conjugated with hydrophilic small molecules for cellular delivery.
COMPOUNDS FOR THE REDUCTION OF BETA-AMYLOID PRODUCTION
-
Page/Page column 45, (2012/02/02)
Compounds of the formula (I) are provided, including pharmaceutically acceptable salts thereof: which modulate β-amyloid peptide (β-AP) production, and are useful in the treatment of Alzheimer's Disease and other conditions affected by -amyloid peptide (β-AP) production.
