84-22-0 Usage
Description
Tetryzoline, also known as Tetrahydrozoline, is a sympathomimetic drug that belongs to the imidazoline family. It is a potent vasoconstrictor and has both alpha-1 and alpha-2 adrenergic agonist properties. Its hydrophilic nature allows it to easily cross the blood-brain barrier, making it a potential candidate for various medical applications.
Source:
Tetryzoline is typically synthesized through a series of chemical reactions involving imidazole and other precursors.
Production Methods:
The production of Tetryzoline involves a series of chemical reactions, including the formation of imidazole rings and subsequent functionalization to introduce the desired substituents.
Uses
Used in Ophthalmology:
Tetryzoline is used as an ocular vasoconstrictor for the temporary relief of redness and irritation in the eyes. It works by constricting the blood vessels in the eye, reducing blood flow and alleviating the redness caused by various conditions such as allergies, conjunctivitis, and eye strain.
Used in Emergency Medicine:
Tetryzoline is used as a diagnostic tool in emergency medicine to differentiate between different types of shock. By administering Tetryzoline and observing the patient's response, medical professionals can determine the underlying cause of the shock and initiate appropriate treatment.
Used in Dermatology:
Tetryzoline is used topically as a vasoconstrictor for the treatment of minor inflammations, insect bites, and skin irritations. Its vasoconstrictive properties help reduce swelling, redness, and itching associated with these conditions.
Synthesis
Tetrahydrozoline, 2-(1,2,3,4-tetrahydro-1-naphthalenyl)-2-imidazoline
(11.1.41), is synthesized in one step by the heterocyclization of 1-cyanotetraline with ethylenediamine [45].
Check Digit Verification of cas no
The CAS Registry Mumber 84-22-0 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 8 and 4 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 84-22:
(4*8)+(3*4)+(2*2)+(1*2)=50
50 % 10 = 0
So 84-22-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H16N2/c1-2-6-11-10(4-1)5-3-7-12(11)13-14-8-9-15-13/h1-2,4,6,12H,3,5,7-9H2,(H,14,15)
84-22-0Relevant articles and documents
Feed additive for improving growth in agricultural animals
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, (2008/06/13)
By using α-mimetics, particularly compounds of general formulae I to III and the compounds listed in Table I, as feed additives in fattening animals, it has surprisingly been possible to improve the daily weight gain, the utilisation of fodder and the ratio of muscle to fat in favor of the proportion of muscle and protein.