84680-75-1

Basic information

• Product Name: ASTRAGALOSIDE I
• Synonyms: 20,24-EPOXYCYCLOARTANE-3,16,25-TRIOL-6-O-BETA-D-GLUCOPYRANOSIDE;ASTRAGALOSIDE I;ASTRAGALOSIDE I(SH);Astrasieversianin IV;Cyclosieversioside B;Cyclosiversioside B;Astragaloside l, 98%, from Astragalus membranaceus Bunge
• CAS NO: 84680-75-1
• Molecular Formula: C₄₅H₇₂O₁₆
• Molecular Weight: 840.99
• Product Categories: Miscellaneous Natural Products;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 84680-75-1.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 910.64 °C at 760 mmHg
• Flash Point: 265.49 °C
• Appearance: white crystal
• Density: 1.39 g/cm³
• Refractive Index: 1.603
• Storage Temp.: 2-8°C(protect from light)
• Solubility: Methanol (Slightly), Pyridine (Slightly)
• PKA: 12.87±0.70(Predicted)
• CAS DataBase Reference: ASTRAGALOSIDE I(CAS DataBase Reference)
• NIST Chemistry Reference: ASTRAGALOSIDE I(84680-75-1)
• EPA Substance Registry System: ASTRAGALOSIDE I(84680-75-1)

Safety Data

• Hazardous Substances Data: 84680-75-1(Hazardous Substances Data)

Usage

Description

Astragaloside I, a saponin compound derived from the Astragalus membranaceus plant, is known for its diverse range of biological activities and potential health benefits. It possesses cardioprotective properties and has been found to enhance cognitive function, making it a valuable component in both traditional medicine and modern pharmaceutical applications.

Uses

Used in Pharmaceutical Industry:
Astragaloside I is used as a cardioprotective agent for its ability to protect the heart from various stressors and improve overall cardiovascular health. Its cardioprotective effects are attributed to its antioxidant, anti-inflammatory, and anti-apoptotic properties, which help maintain the integrity and function of the heart.
Astragaloside I is also used as a cognitive enhancer for its potential to improve cognitive function and support brain health. It has been shown to promote neurogenesis, enhance synaptic plasticity, and protect against neurodegeneration, making it a promising candidate for the treatment of cognitive disorders and age-related cognitive decline.
In addition to its cardioprotective and cognitive-enhancing properties, Astragaloside I has been studied for its potential applications in other areas of health and medicine, such as immune modulation, anti-inflammatory effects, and anti-tumor activity. Its diverse range of biological activities highlights its potential as a versatile and valuable compound in the development of new therapeutic agents.

InChI:InChI=1/C43H68O16/c1-20(45)54-33-25(48)18-53-37(34(33)55-21(2)46)56-22-8-11-42-19-43(42)13-12-39(5)35(41(7)10-9-29(59-41)38(3,4)52)24(47)16-40(39,6)28(43)15-26(23(42)14-22)57-36-32(51)31(50)30(49)27(17-44)58-36/h22-37,44,47-52H,8-19H2,1-7H3/t22-,23?,24-,25+,26-,27+,28-,29-,30+,31-,32+,33-,34+,35-,36+,37-,39+,40-,41+,42+,43+/m0/s1

Downstream Products

• 83207-58-3 cyclosiversioside F 
• 86541-79-9 astragenol 
• 84605-18-5 cycloastragenol 
• 83207-58-3 astragaloside IV