849243-26-1

Basic information

• Product Name: 1-Pyrrolidineheptanenitrile, 2-[(1E)-4,4-difluoro-3-oxo-4-phenyl-1-butenyl]-5-oxo-, (2R)-
• CAS NO: 849243-26-1
• Molecular Formula: C21H24F2N2O2
• Molecular Weight: 374.431
• Mol File: 849243-26-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Pyrrolidineheptanenitrile, 2-[(1E)-4,4-difluoro-3-oxo-4-phenyl-1-butenyl]-5-oxo-, (2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolidineheptanenitrile, 2-[(1E)-4,4-difluoro-3-oxo-4-phenyl-1-butenyl]-5-oxo-, (2R)-(849243-26-1)
• EPA Substance Registry System: 1-Pyrrolidineheptanenitrile, 2-[(1E)-4,4-difluoro-3-oxo-4-phenyl-1-butenyl]-5-oxo-, (2R)-(849243-26-1)

Safety Data

• Hazardous Substances Data: 849243-26-1(Hazardous Substances Data)

Upstream product

• 346672-63-7 7-[(2R)-2-formyl-5-oxopyrrolidin-1-yl]heptanenitrile 
• 82302-97-4 dimethyl (3,3-difluoro-2-oxo-3-phenylpropyl)phosphonate 
• 346672-94-4 7-[(2R)-2-({[tert-butyl(dimethyl)silyl]oxy}methyl)-5-oxopyrrolidin-1-yl]heptanenitrile 
• 346672-95-5 7-[(2R)-2-hydroxymethyl-5-oxopyrrolidin-1-yl]heptanenitrile 
• 128899-30-9 (R)-5-(((tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one 
• 2248-46-6 ethyl 2,2-difluoro-2-phenylacetate 
• 20965-27-9 7-bromo-heptanonitrile 
• 1603-79-8 phenylglyoxylic acid ethyl ester 

Downstream Products

• 849243-29-4 7-{(2R)-2-[(1E,3R)-4,4-difluoro-3-hydroxy-4-phenylbut-1-en-1-yl]-5-oxopyrrolidin-1-yl}heptanenitrile 
• 849243-27-2 7-{(2R)-2-[(1E,3S)-4,4-difluoro-3-hydroxy-4-phenylbut-1-en-1-yl]-5-oxopyrrolidin-1-yl}heptanenitrile 

Relevant articles and documents

Discovery and synthesis of a potent, selective and orally bioavailable EP4 receptor agonist

An optimized analog of prostaglandin E2 which incorporates a γ-lactam in place of the cyclopentanone ring and which incorporates metabolically stabilized side chains, has been identified and shown to exhibit potent and selective EP4 receptor ag