84928-46-1Relevant articles and documents
Synthesis of a novel class of cdc25A inhibitors from Vitamin D3
Dodo, Kosuke,Takahashi, Masato,Yamada, Yuji,Sugimoto, Yoshikazu,Hashimoto, Yuichi,Shirai, Ryuichi
, p. 615 - 617 (2000)
We have developed a novel class of cdc25A inhibitors by drastic modification of hydrophobic and hydrophillic substructures of dysidiolide. The unsaturated derivative 3b strongly inhibited cdc25A (IC50=7.7 μM) and caused G1 arrest of HL60 cells. (C) 2000 Elsevier Science Ltd. All rights reserved.